Clinical trial • Phase III • Oncology

Cevostamab for Relapsed or refractory multiple myeloma

Phase III trial of Cevostamab for Relapsed or refractory multiple myeloma. 35 participants.

Overview

Trial Therapeutic Area
Oncology
Trial Disease
Relapsed or refractory multiple myeloma
Trial Stage
Phase III
Drug Modality
Monoclonal antibody

Key dates

Initial CTIS Submission Date
08-07-2024
First CTIS Authorization Date
30-07-2024

Trial design

Phase III trial across 6 sites in Belgium, Greece, Italy.

Target Sample Size
35

Eligibility

Recruits 35 Vulnerable population selected; no details on consent or assent handling are provided in the available record..

Vulnerable Population
Vulnerable population selected; no details on consent or assent handling are provided in the available record.

Recruitment

Planned Sample Size
35
Recruitment Window Months
49
Consent Approach
No information on the informed consent or assent process is provided in the available record; vulnerable population selection is indicated but age-specific consent/assent documents or languages are not described.

Geography

Total Number Of Sites
6
Total Number Of Participants
45

Belgium

Earliest CTIS Part Ii Submission Date
17-01-2023
Latest Decision Or Authorization Date
07-07-2025
Processing Time Days
902
Number Of Sites
2
Number Of Participants
12

Sites

Site Name
Universitair Ziekenhuis Gent
Department Name
Hematology
Contact Person Name
Nicolas Kint
Contact Person Email
nicolas.kint@uzgent.be
Site Name
UZ Brussel
Department Name
Hematology
Contact Person Name
Henri Schots
Contact Person Email
rik.schots@uzbrussel.be

Greece

Earliest CTIS Part Ii Submission Date
17-01-2023
Latest Decision Or Authorization Date
28-01-2026
Processing Time Days
1107
Number Of Sites
2
Number Of Participants
20

Sites

Site Name
Alexandra Hospital
Department Name
Athens Medical School - Therapeutic Clinic
Contact Person Name
Meletios-Athanasios Dimopoulos
Contact Person Email
mdimop@med.uoa.gr
Site Name
Evangelismos S.A.
Department Name
Hematology Clinic
Contact Person Name
Sosana Delimpasi
Contact Person Email
sodeli@yahoo.com

Italy

Earliest CTIS Part Ii Submission Date
17-01-2023
Latest Decision Or Authorization Date
28-01-2026
Processing Time Days
1107
Number Of Sites
2
Number Of Participants
13

Sites

Site Name
Humanitas Mirasole S.p.A.
Department Name
U.O di Oncologia Medica ed Ematologia accreditata fase I
Contact Person Name
Armando Santoro
Site Name
Azienda Ospedaliero-Universitaria Di Bologna IRCCS Istituto Di Ricerca E Di Cura A Carattere Scientifico
Department Name
U.O. di Ematologia
Contact Person Name
Elena Zamagni
Contact Person Email
e.zamagni@unibo.it

Sponsor

Primary sponsor

Full Name
Genentech Inc.
Organisation Type
Pharmaceutical company
Country Of Registered Address
United States

Investigational products

Investigational Product Name
Cevostamab (BFCR4350A)
Active Substance
Cevostamab
Modality
Monoclonal antibody
Routes Of Administration
Subcutaneous
Route
Subcutaneous

Related trials

Other published trials that may interest you.