Clinical trial • Phase III • Other

andexanet alfa for Healthy volunteers

Phase III trial of andexanet alfa for Healthy volunteers. 78 participants.

Overview

Trial Therapeutic Area
Other
Trial Disease
Healthy volunteers
Trial Stage
Phase III
Drug Modality
Peptide/protein/enzyme

Key dates

Initial CTIS Submission Date
17-10-2025
First CTIS Authorization Date
09-01-2026

Trial design

Phase III trial across 1 site in Germany.

Target Sample Size
78

Eligibility

Recruits 78 Vulnerable population selected; no consent or assent details provided in source documents..

Vulnerable Population
Vulnerable population selected; no consent or assent details provided in source documents.

Recruitment

Planned Sample Size
78
Recruitment Window Months
3
Consent Approach
No informed consent or assent details provided; vulnerable population selected.

Geography

Total Number Of Sites
1
Total Number Of Participants
108

Germany

Earliest CTIS Part Ii Submission Date
24-11-2025
Latest Decision Or Authorization Date
09-01-2026
Processing Time Days
46
Number Of Sites
1
Number Of Participants
108

Sites

Site Name
Klinikum Westend Haus 31, Spandauer Damm 130, Charlottenburg
Department Name
2601; Parexel Early Phase Unit Berlin
Contact Person Name
Bartlomiej Kozak
Contact Person Email
bartlomiej.kozak@parexel.com

Sponsor

Primary sponsor

Full Name
AstraZeneca AB
Organisation Type
Pharmaceutical company
Country Of Registered Address
Sweden

Contract research organisations

Name
PAREXEL International GmbH

Investigational products

Investigational Product Name
andexanet alfa
Active Substance
andexanet alfa
Modality
Peptide/protein/enzyme

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