Clinical trial • Phase II • Other

Naproxen sodium for Healthy volunteers

Phase II trial of Naproxen sodium for Healthy volunteers.

Overview

Trial Therapeutic Area
Other
Trial Disease
Healthy volunteers
Trial Stage
Phase II
Drug Modality
Small molecule

Key dates

Initial CTIS Submission Date
01-04-2026
First CTIS Authorization Date
24-04-2026

Trial design

Randomised, open-label, test product naproxen sodium 660 mg modified release tablets vs reference product actromadol 660 mg modified-release tablets (both 660 mg modified-release oral tablets as stated in title)-controlled, crossover Phase II trial across 1 site in Czechia.

Randomised
Yes
Open Label
Yes
Comparator
Test Product Naproxen sodium 660 mg modified release tablets vs Reference Product Actromadol 660 mg Modified-Release tablets (both 660 mg modified-release oral tablets as stated in title)
Crossover
Yes
Target Sample Size
32
Trial Duration For Participant
31

Eligibility

Recruits 32 Vulnerable population selected (isVulnerablePopulationSelected = true). No further details on consent or assent handling available in the record..

Vulnerable Population
Vulnerable population selected (isVulnerablePopulationSelected = true). No further details on consent or assent handling available in the record.

Recruitment

Planned Sample Size
32
Recruitment Window Months
1

Geography

Total Number Of Sites
1
Total Number Of Participants
32

Czechia

Earliest CTIS Part Ii Submission Date
26-03-2026
Latest Decision Or Authorization Date
11-05-2026
Processing Time Days
46
Number Of Sites
1
Number Of Participants
32

Sites

Site Name
Quinta-Analytica s.r.o.
Department Name
Clinical Unit
Contact Person Name
Jiří Juchelka
Contact Person Email
jiri.juchelka@quinta.cz

Sponsor

Primary sponsor

Full Name
Laboratorios Cinfa S.A.
Organisation Type
Pharmaceutical company
Country Of Registered Address
Spain

Investigational products

Investigational Product Name
Test Product Naproxen sodium 660 mg modified release tablets
Active Substance
Naproxen sodium
Modality
Small molecule
Routes Of Administration
oral
Route
oral
Starting Dose
660 mg
Dose Levels
660 mg
Frequency
multiple-dose
Investigational Product Name
Reference Product Actromadol 660 mg Modified-Release tablets
Modality
Small molecule
Routes Of Administration
oral
Route
oral
Starting Dose
660 mg
Dose Levels
660 mg
Frequency
multiple-dose

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