Clinical trial • Phase III • Other

Tadalafil for Healthy volunteers

Phase III trial of Tadalafil for Healthy volunteers.

Overview

Trial Therapeutic Area
Other
Trial Disease
Healthy volunteers
Trial Stage
Phase III
Drug Modality
Small molecule

Key dates

Initial CTIS Submission Date
17-03-2026
First CTIS Authorization Date
29-04-2026

Trial design

Randomised, two tadalafil formulations: tadalafil oral suspension, single oral dose 20 mg (fasting) versus tadalafil film-coated tablets, single oral dose 20 mg (fasting).-controlled, crossover Phase III trial across 1 site in Spain.

Randomised
Yes
Comparator
Two tadalafil formulations: tadalafil oral suspension, single oral dose 20 mg (fasting) versus tadalafil film-coated tablets, single oral dose 20 mg (fasting).
Crossover
Yes
Target Sample Size
8

Eligibility

Recruits 8 No vulnerable populations selected; trial involves healthy adult male volunteers only; no consent/assent details provided..

Vulnerable Population
No vulnerable populations selected; trial involves healthy adult male volunteers only; no consent/assent details provided.

Recruitment

Planned Sample Size
8
Recruitment Window Months
1

Geography

Total Number Of Sites
1
Total Number Of Participants
8

Spain

Earliest CTIS Part Ii Submission Date
15-04-2026
Latest Decision Or Authorization Date
30-04-2026
Processing Time Days
15
Number Of Sites
1
Number Of Participants
8

Sites

Site Name
Hospital Clinico San Carlos
Department Name
Farmacologia Clinica
Contact Person Name
Antonio Portolés Perez
Contact Person Email
ufase1fc.hcsc@salud.madrid.org
Number Of Participants
8

Sponsor

Primary sponsor

Full Name
Farmalider S.A.
Organisation Type
Pharmaceutical company
Country Of Registered Address
Spain

Investigational products

Investigational Product Name
Tadalafil oral suspension
Active Substance
Tadalafil
Modality
Small molecule
Routes Of Administration
oral
Route
oral
Starting Dose
20 mg
Dose Levels
20 mg (single dose)
Frequency
single oral dose
Maximum Dose
20 mg
Investigational Product Name
Tadalafil film-coated tablets
Active Substance
Tadalafil
Modality
Small molecule
Routes Of Administration
oral
Route
oral
Starting Dose
20 mg
Dose Levels
20 mg (single dose)
Frequency
single oral dose
Maximum Dose
20 mg

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