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EU · Phase III · Myeloid neoplasms

EU Phase III myeloid neoplasms: sites, PIs and CROs

Bologna participated in 13 of 22 Phase III myeloid neoplasm trials. Alessandra Iurlo participated in six, with five other investigators also leading the myeloid neoplasm trial network. IQVIA and Parexel supported five programs each. Twenty-one trials are authorised.

22Phase III myeloid neoplasm trials
602distinct EU sites
1,071named investigators

Countries

Spain appears in 19 trials

Germany and France each participate in 18 trials. Germany carries the largest site footprint among the five leading countries.

Leading countries by trial participation
Spain275 site appearances19
Germany280 site appearances18
France239 site appearances18
Italy208 site appearances15
Belgium75 site appearances13

Sites

Bologna participates in 13 trials

AP-HP, CHU Bordeaux, CHU Nice and Vall d’Hebron each participated in 12.

Leading sites by trial participation
AOU Bologna IRCCSItaly13
Assistance Publique Hôpitaux de ParisFrance12
CHU BordeauxFrance12
CHU NiceFrance12
Hospital Universitari Vall d’HebronSpain12

Investigators

Alessandra Iurlo leads with six trials

Five other investigators also participated in six Phase III myeloid neoplasm trials.

Leading investigators by trial participation
Alessandra IurloItaly6
Alessandro LucchesiItaly6
Blanca Xicoy CiriciSpain6
Fabrizio PaneItaly6
Massimo BrecciaItaly6
Sebastian GrosickiPoland6

CROs

IQVIA and Parexel support five programs

Syneos Health supports four programs, followed by ICON and PPD with three each.

CROs by Phase III programs supported
IQVIA5
Parexel5
Syneos Health4
ICON3
PPD3

Active trial footprint

21 trials are authorised

Fifteen recruit in at least one EU country. The authorised trials span 1,527 sites and 7,189 planned participants, averaging 72.7 sites, 8.9 countries and 342 planned participants per trial.

Authorised Phase III trials by disease
Acute myeloid leukemia10
Myelofibrosis5
Chronic myeloid leukemia2
Polycythemia vera2
Acute promyelocytic leukemia1
Myelodysplastic syndromes1

Source: CTIS trial records and trial documents, reviewed 22 September 2026.

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