Clinical trial • Phase III • Gastroenterology
LINAPRAZAN GLURATE for Erosive esophagitis due to gastroesophageal reflux disease (GERD)
Phase III trial of LINAPRAZAN GLURATE for Erosive esophagitis due to gastroesophageal reflux disease (GERD).
Overview
- Trial Therapeutic Area
- Gastroenterology
- Trial Disease
- Erosive esophagitis due to gastroesophageal reflux disease (GERD)
- Trial Stage
- Phase III
- Drug Modality
- Small molecule
Key dates
- Initial CTIS Submission Date
- 19-12-2025
- First CTIS Authorization Date
- 28-04-2026
Trial design
Randomised, lansoprazole; dose and schedule not specified in english documentation-controlled Phase III trial across 71 sites in Bulgaria, Czechia, Germany and others.
- Randomised
- Yes
- Comparator
- Lansoprazole; dose and schedule not specified in English documentation
- Target Sample Size
- 96
- Trial Duration For Participant
- 378
Eligibility
Recruits 96 No vulnerable population selected. Participants must understand and voluntarily sign an Informed Consent Form (ICF) prior to initiation of any trial-related assessments/procedures. No assent/consent procedures for minors are described..
- Pregnancy Exclusion
- 11. Women who are pregnant or breast feeding
- Vulnerable Population
- No vulnerable population selected. Participants must understand and voluntarily sign an Informed Consent Form (ICF) prior to initiation of any trial-related assessments/procedures. No assent/consent procedures for minors are described.
Inclusion criteria
- {"criterion_text":"- An individual who has participated in a preceding linaprazan glurate healing trial will be asked to participate in this trial if the following criteria apply: 1. The participant understands and voluntarily signs an Informed Consent Form (ICF) prior to initiation of any trial-related assessments/procedures.\n- 2. The participant has a healed EE as assessed by central review of endoscopic examination either from the last regular visit in a preceding phase 3 healing trial OR from the Run-in Period to the present maintenance trial.\n- 3. The participant is willing and able to comply with all aspects of the protocol (including endoscopies, tablet and capsule swallowing, electronic device [e-device] completion, etc.)."}
Exclusion criteria
- {"criterion_text":"- An individual who has participated in a preceding linaprazan glurate phase 3 healing trial can be enrolled in this maintenance trial unless they meet any of the following exclusion criteria: 1. EE as graded from the endoscopy during the Run-in Period (only applicable for participants with previous endoscopy >14 days before the last regular visit in the preceding healing trial).\n- 10. Current or history of alcohol, drug abuse, and/or use of androgens/anabolic steroids (testosterone and testosterone esters [enanthate, undecanoate, cypionate], methyltestosterone, oxandrolone, stanozolol, fluoxymesterone, danazol, tetrahydrogestrinone, 7α-methyl-19-nortestosterone) within 2 years prior to Run-in Period. Stable androgen substitution treatment for male hypogonadism is allowed.\n- 11. Women who are pregnant or breast feeding\n- 12. Individual is an employee of the Investigator, trial site, Sponsor, or Contract Research Organization (CRO) with direct involvement in the proposed trial or other trials under the direction of that Investigator, trial site, Sponsor, or CRO, as well as family members of the employee of the Investigator, trial site, Sponsor, or CRO.\n- 13. Individuals who have previously participated (completed or withdrawn) in this trial.\n- 14. A female participant of childbearing potential who is or may be sexually active with a non-sterilized male partner and who is unwilling to routinely use highly effective contraception from the signing of the ICF until 7 days after the last dose of IP.\n- 15. A male participant with a partner of childbearing potential who is unwilling to routinely use highly effective contraception and is unwilling to agree to not father a child from the signing of the ICF until at least 7 days after the last dose of IP.\n- 2. Solitary esophageal ulcer in the proximal two-thirds of the esophagus, untreated Barrett’s esophagus or any other condition affecting the esophagus, including eosinophilic esophagitis; esophageal varices; viral or fungal infection; esophageal stricture.\n- 3. Significant noncompliance with protocol-specified procedures or treatment in the preceding healing trial as judged by the Investigator.\n- 4. Adverse event (AE) resulting in premature discontinuation of IP in the preceding healing trial.\n- 5. History or presence of any clinically significant cardiovascular, respiratory, hepatic, renal, gastrointestinal (GI), endocrine, hematological, neurological disease or disorder, or psychiatric diagnosis which, in the opinion of the Investigator, may either put the participant at risk because of participation in the trial, or influence the trial results or the participant’s ability to participate in the trial. The following examples are conditions that would exclude the participant from participating: a. History of myocardial infarction/ acute coronary syndrome within 3 months prior to the M0 visit b. History of ventricular arrhythmia or implanted cardioverter defibrillator c. Symptomatic congestive heart failure (New York Heart Association [NYHA] class 3-4) d. Family history of/ diagnosis of hereditary arrhythmia syndrome\n- 6. History of adult asthma that required intensive treatment in an emergency room\n- 7. Any planned major surgery within 52 weeks of the Run-in Period.\n- 8. Any clinically significant laboratory parameter outside reference value that has occurred since Screening or Baseline values in the preceding healing trial and which, in the opinion of the Investigator, may suggest a new or insufficiently understood disease, may present an unreasonable risk to the participant as a result of his/her participation in the trial, or may interfere with trial assessments. The below laboratory test results during the Run-in Period* (HX/M0 visit) are exclusionary: a. Serum alanine aminotransferase (ALT) or aspartate aminotransferase (AST) > 1.5 × upper limit of normal (ULN) for the central laboratory conducting the test. b. Serum total bilirubin (TBL) >1.5 × ULN for the central laboratory conducting the test. (individuals with Gilbert’s syndrome can be included). *Note: One retest is allowed during the Run-in Period.\n- 9. Enrollment in another interventional clinical trial, except for ongoing participation in an EE healing trial with linaprazan glurate."}
Endpoints
Primary endpoints
- {"endpoint_text":"- 1.Maintained healing of EE after 24 weeks as assessed by central reading of endoscopy.","definition_or_measurement_approach":"Assessed by central reading of endoscopy."}
Secondary endpoints
- {"endpoint_text":"- 1. Maintained healing of EE after 24 weeks as assessed by central reading of endoscopy","definition_or_measurement_approach":"Assessed by central reading of endoscopy."}
- {"endpoint_text":"- 2. Maintained healing from EE as assessed by central reading of endoscopy after 24 weeks in participants with Baseline EE due to GERD of LA grades C/D.","definition_or_measurement_approach":"Assessed by central reading of endoscopy in subgroup with baseline LA grades C/D."}
- {"endpoint_text":"- 3. Percentage of heartburn-free days from Baseline to Week 24 based on electronic Diary","definition_or_measurement_approach":"Participant-reported via electronic diary; percentage of 24-hour heartburn-free days from baseline to Week 24."}
- {"endpoint_text":"- 4. Maintained healing of EE comparing linaprazan glurate ‘high dose’ with lansoprazole after 52 weeks as assessed by central reading of endoscopy.","definition_or_measurement_approach":"Assessed by central reading of endoscopy at Week 52 comparing linaprazan glurate high dose vs lansoprazole."}
- {"endpoint_text":"- 5. Maintained healing of EE comparing linaprazan glurate ‘low dose’ with lansoprazole after 52 weeks as assessed by central reading of endoscopy","definition_or_measurement_approach":"Assessed by central reading of endoscopy at Week 52 comparing linaprazan glurate low dose vs lansoprazole."}
Recruitment
- Planned Sample Size
- 96
- Recruitment Window Months
- 44
- Consent Approach
- Participants must 'understand and voluntarily sign an Informed Consent Form (ICF) prior to initiation of any trial-related assessments/procedures.' ICF and related documents (including pregnancy follow-up ICF) are available in multiple languages (EN, DE, PL, HU, RO, BUL and others) as indicated in the submitted documents.
Geography
- Total Number Of Sites
- 71
- Total Number Of Participants
- 96
Bulgaria
- Earliest CTIS Part Ii Submission Date
- 27-03-2026
- Latest Decision Or Authorization Date
- 04-05-2026
- Processing Time Days
- 38
- Number Of Sites
- 18
- Number Of Participants
- 18
Sites
- Site Name
- Multiprofile Hospital For Active Treatment Vita Ltd.
- Department Name
- Department of Gastroenterology
- Principal Investigator Name
- Vasil Koynarski
- Principal Investigator Email
- v.koynarski_2024@abv.bg
- Contact Person Name
- Vasil Koynarski
- Contact Person Email
- v.koynarski_2024@abv.bg
- Site Name
- Diagnostic Consultation Center XX-Sofia EOOD
- Principal Investigator Name
- Dimitar Dimitrov
- Principal Investigator Email
- dr.dimitar.dimitrov.mg@gmail.com
- Contact Person Name
- Dimitar Dimitrov
- Contact Person Email
- dr.dimitar.dimitrov.mg@gmail.com
- Site Name
- Multiprofile Hospital For Active Treatment Sveti Ivan Rilski 2003 OOD
- Department Name
- Department of Internal Medicine
- Principal Investigator Name
- Vasil Bachev
- Principal Investigator Email
- vas_bachev@abv.bg
- Contact Person Name
- Vasil Bachev
- Contact Person Email
- vas_bachev@abv.bg
- Site Name
- Diagnostic Consulting Center 1 Sliven EOOD
- Principal Investigator Name
- Dimitar Pavlov
- Principal Investigator Email
- dr.pavlov.dimitar@gmail.com
- Contact Person Name
- Dimitar Pavlov
- Contact Person Email
- dr.pavlov.dimitar@gmail.com
- Site Name
- Dkc Fokus-5 Lzip OOD
- Principal Investigator Name
- Naiden Kandilarov
- Principal Investigator Email
- naidenk@mail.bg
- Contact Person Name
- Naiden Kandilarov
- Contact Person Email
- naidenk@mail.bg
- Site Name
- Medical Center Hera - Kyustendil EOOD
- Principal Investigator Name
- Kameliya Grigorova-Georgieva
- Principal Investigator Email
- dr.kameliyageorgieva@mail.bg
- Contact Person Name
- Kameliya Grigorova-Georgieva
- Contact Person Email
- dr.kameliyageorgieva@mail.bg
- Site Name
- MBAL Sveta Karidad EAD
- Department Name
- Department of Gastroenterology
- Principal Investigator Name
- Simon Sariyan
- Principal Investigator Email
- dr.s.sarian@abv.bg
- Contact Person Name
- Simon Sariyan
- Contact Person Email
- dr.s.sarian@abv.bg
- Site Name
- Medical Centre Futuremeds EOOD
- Principal Investigator Name
- Vesela Georgieva
- Principal Investigator Email
- vesela.georgieva@futuremeds.bg
- Contact Person Name
- Vesela Georgieva
- Contact Person Email
- vesela.georgieva@futuremeds.bg
- Site Name
- Uniteversity Muliprofile Hospital For Active Treatment Tsaritsa Yoanna-Isul EAD
- Department Name
- Gastroenterology Clinic
- Principal Investigator Name
- Mila Kovacheva – Slavova
- Principal Investigator Email
- kovacheva.mila@gmail.com
- Contact Person Name
- Mila Kovacheva – Slavova
- Contact Person Email
- kovacheva.mila@gmail.com
- Site Name
- Medical Center Hera EOOD
- Principal Investigator Name
- Ivan Popadiyn
- Principal Investigator Email
- ivan.popadiin@heraclinics.com
- Contact Person Name
- Ivan Popadiyn
- Contact Person Email
- ivan.popadiin@heraclinics.com
- Site Name
- University Multiprofile Hospital For Active Treatment And Emergency Medicine N I Pirogov
- Department Name
- Department of Gastroenterology
- Principal Investigator Name
- Kamen Danov
- Principal Investigator Email
- dr.danov@main.bg
- Contact Person Name
- Kamen Danov
- Contact Person Email
- dr.danov@main.bg
- Site Name
- UMHAT Sveta Marina Pleven OOD
- Department Name
- Department of Gastroenterology
- Principal Investigator Name
- Zornitsa Gorcheva
- Principal Investigator Email
- gorcheva@fhsmo.com
- Contact Person Name
- Zornitsa Gorcheva
- Contact Person Email
- gorcheva@fhsmo.com
- Site Name
- Multiprofile Hospital For Active Treatment St. Ivan Rilski Gorna Oriahovitsa EOOD
- Department Name
- First Department of Internal Medicine
- Principal Investigator Name
- Ilko Kosturkov
- Principal Investigator Email
- ikosturkov@mcmedicaplus.com
- Contact Person Name
- Ilko Kosturkov
- Contact Person Email
- ikosturkov@mcmedicaplus.com
- Site Name
- Purva Chastna Mbal EOOD Vratsa
- Department Name
- Department of Internal Medicine
- Principal Investigator Name
- Dobromir Dragoychev
- Principal Investigator Email
- dr_dragoichev@abv.bg
- Contact Person Name
- Dobromir Dragoychev
- Contact Person Email
- dr_dragoichev@abv.bg
- Site Name
- Diagnostic-Consultative Center Alexandrovska EOOD
- Principal Investigator Name
- Diana Stefanova– Petrova
- Principal Investigator Email
- prof.petrova@mail.bg
- Contact Person Name
- Diana Stefanova– Petrova
- Contact Person Email
- prof.petrova@mail.bg
- Site Name
- Medical center Orange Ltd.
- Principal Investigator Name
- Dimitar Stoyanov
- Principal Investigator Email
- stoyanov.md@mail.bg
- Contact Person Name
- Dimitar Stoyanov
- Contact Person Email
- stoyanov.md@mail.bg
- Site Name
- Multiprofile Hospital For Active Treatment St Panteleimon Plovdiv Ltd.
- Department Name
- Department of Gastroenterology
- Principal Investigator Name
- Dimitar Terziev
- Principal Investigator Email
- dr.dimitar.terziev@gmail.com
- Contact Person Name
- Dimitar Terziev
- Contact Person Email
- dr.dimitar.terziev@gmail.com
- Site Name
- University Multiprofile Hospital For Active Treatment St. Ivan Rilski EAD
- Department Name
- Gastroenterology Clinic
- Principal Investigator Name
- Rosen Nikolov
- Principal Investigator Email
- roskinlk@gmail.com
- Contact Person Name
- Rosen Nikolov
- Contact Person Email
- roskinlk@gmail.com
Czechia
- Earliest CTIS Part Ii Submission Date
- 27-03-2026
- Latest Decision Or Authorization Date
- 28-04-2026
- Processing Time Days
- 32
- Number Of Sites
- 7
- Number Of Participants
- 7
Sites
- Site Name
- Vojenska Nemocnice Brno
- Department Name
- Interní oddělení
- Principal Investigator Name
- David Štěpek
- Principal Investigator Email
- dstepek@vnbrno.cz
- Contact Person Name
- David Štěpek
- Contact Person Email
- dstepek@vnbrno.cz
- Site Name
- SurGal Clinic s.r.o.
- Department Name
- Oddělení chirurgie
- Principal Investigator Name
- Jan Ulbrych
- Principal Investigator Email
- ulbrych.jan@surgalclinic.cz
- Contact Person Name
- Jan Ulbrych
- Contact Person Email
- ulbrych.jan@surgalclinic.cz
- Site Name
- PreventaMed s.r.o.
- Department Name
- Interní ambulance
- Principal Investigator Name
- Jiří Pumprla
- Principal Investigator Email
- pumprla@vilazdravi.cz
- Contact Person Name
- Jiří Pumprla
- Contact Person Email
- pumprla@vilazdravi.cz
- Site Name
- Fakultni Nemocnice Brno
- Department Name
- Interní gastroenterologická klinika a endoskopické centrum
- Principal Investigator Name
- Štefan Konečný
- Principal Investigator Email
- konecny.stefan@fnbrno.cz
- Contact Person Name
- Štefan Konečný
- Contact Person Email
- konecny.stefan@fnbrno.cz
- Site Name
- Endohope Morava s.r.o.
- Department Name
- Gastroenterologie
- Principal Investigator Name
- Evžen Machytka
- Principal Investigator Email
- machytka@endohope.cz
- Contact Person Name
- Evžen Machytka
- Contact Person Email
- machytka@endohope.cz
- Site Name
- Gastromedic s.r.o.
- Principal Investigator Name
- Václav Leksa
- Principal Investigator Email
- vaclav.leksa@seznam.cz
- Contact Person Name
- Václav Leksa
- Contact Person Email
- vaclav.leksa@seznam.cz
- Site Name
- Nemocnice Prachatice a.s.
- Department Name
- Gastroenterologická ambulance
- Principal Investigator Name
- Pavel Lipták
- Principal Investigator Email
- pavel.liptak@nempt.cz
- Contact Person Name
- Pavel Lipták
- Contact Person Email
- pavel.liptak@nempt.cz
Germany
- Earliest CTIS Part Ii Submission Date
- 21-01-2026
- Latest Decision Or Authorization Date
- 29-04-2026
- Processing Time Days
- 98
- Number Of Sites
- 5
- Number Of Participants
- 5
Sites
- Site Name
- Diako Mannheim gGmbH
- Principal Investigator Name
- Dieter Schilling
- Principal Investigator Email
- d.schilling@bbtgruppe.de
- Contact Person Name
- Dieter Schilling
- Contact Person Email
- d.schilling@bbtgruppe.de
- Site Name
- Private Practice for Gastroenterology
- Principal Investigator Name
- Wolfgang Reindl
- Principal Investigator Email
- wr@hd-gastro.de
- Contact Person Name
- Wolfgang Reindl
- Contact Person Email
- wr@hd-gastro.de
- Site Name
- Eugastro GmbH
- Principal Investigator Name
- Ingolf Schiefke
- Principal Investigator Email
- ingolf.schiefke@eugastro.de
- Contact Person Name
- Ingolf Schiefke
- Contact Person Email
- ingolf.schiefke@eugastro.de
- Site Name
- Medical Care Unit Dachau
- Principal Investigator Name
- Wilfred Landry
- Principal Investigator Email
- landry@dachau-med.de
- Contact Person Name
- Wilfred Landry
- Contact Person Email
- landry@dachau-med.de
- Site Name
- MVZ CCB Frankfurt Und Main-Taunus GbR
- Principal Investigator Name
- Mate Knabe
- Principal Investigator Email
- knabe@gastroenterologie-frankfurt.de
- Contact Person Name
- Mate Knabe
- Contact Person Email
- knabe@gastroenterologie-frankfurt.de
Hungary
- Earliest CTIS Part Ii Submission Date
- 21-01-2026
- Latest Decision Or Authorization Date
- 04-05-2026
- Processing Time Days
- 103
- Number Of Sites
- 9
- Number Of Participants
- 9
Sites
- Site Name
- Fejer Varmegyei Szent Gyoergy Egyetemi Oktato Korhaz
- Department Name
- Department of Internal Medicine I
- Principal Investigator Name
- Roland Fejes
- Principal Investigator Email
- rfejes@mail.fmkorhaz.hu
- Contact Person Name
- Roland Fejes
- Contact Person Email
- rfejes@mail.fmkorhaz.hu
- Site Name
- Bekes Varmegyei Koezponti Korhaz
- Department Name
- 4th Department of Internal Medicine - Gastroenterology - Hepatology
- Principal Investigator Name
- Marta Varga
- Principal Investigator Email
- gasztrobcs@bmkk.eu
- Contact Person Name
- Marta Varga
- Contact Person Email
- gasztrobcs@bmkk.eu
- Site Name
- Clinexpert Kft.
- Principal Investigator Name
- Zsanett Zsuzsanna Heringh
- Principal Investigator Email
- info@clinexpert.hu
- Contact Person Name
- Zsanett Zsuzsanna Heringh
- Contact Person Email
- info@clinexpert.hu
- Site Name
- Javorszky Oedoen Korhaz
- Department Name
- Department of Gastroenterology
- Principal Investigator Name
- Tibor Szaloki
- Principal Investigator Email
- szalokitdr@javorszky.hu
- Contact Person Name
- Tibor Szaloki
- Contact Person Email
- szalokitdr@javorszky.hu
- Site Name
- University Of Szeged
- Department Name
- Western Site Department of Internal Medicine
- Principal Investigator Name
- Andras Rosztoczy
- Principal Investigator Email
- rosztoczy.andras@med.u-szeged.hu
- Contact Person Name
- Andras Rosztoczy
- Contact Person Email
- rosztoczy.andras@med.u-szeged.hu
- Site Name
- G1 Intezet Kft.
- Principal Investigator Name
- Levente Balint
- Principal Investigator Email
- info@g1intezet.hu
- Contact Person Name
- Levente Balint
- Contact Person Email
- info@g1intezet.hu
- Site Name
- Central Hospital Of Northern Pest Military Hospital
- Department Name
- Department of Gastroenterology Podmaniczky u. 111.
- Principal Investigator Name
- Tibor Gyokeres
- Principal Investigator Email
- epchk@epc-honvedkorhaz.hu
- Contact Person Name
- Tibor Gyokeres
- Contact Person Email
- epchk@epc-honvedkorhaz.hu
- Site Name
- Vasutegeszseguegyi Nonprofit Koezhasznu Kft.
- Department Name
- Department of Gastroenterology
- Principal Investigator Name
- Gyula G. Kiss
- Principal Investigator Email
- titkarsag@vasuteu.hu
- Contact Person Name
- Gyula G. Kiss
- Contact Person Email
- titkarsag@vasuteu.hu
- Site Name
- Clinexpert Kft. (additional site listing)
- Principal Investigator Name
- Zsanett Zsuzsanna Heringh
- Principal Investigator Email
- info@clinexpert.hu
- Contact Person Name
- Zsanett Zsuzsanna Heringh
- Contact Person Email
- info@clinexpert.hu
Romania
- Earliest CTIS Part Ii Submission Date
- 10-03-2026
- Latest Decision Or Authorization Date
- 04-05-2026
- Processing Time Days
- 55
- Number Of Sites
- 3
- Number Of Participants
- 6
Sites
- Site Name
- Spitalul Clinic Judetean De Urgenta Cluj
- Department Name
- Internal Medicine III
- Principal Investigator Name
- Dan Lucian Dumitrascu
- Principal Investigator Email
- ddumitrascu@umfcluj.ro
- Contact Person Name
- Dan Lucian Dumitrascu
- Contact Person Email
- ddumitrascu@umfcluj.ro
- Site Name
- Tvm Med Serv S.R.L.
- Department Name
- Gastroenterology
- Principal Investigator Name
- Marcel Tantau
- Principal Investigator Email
- mtantau@gmail.com
- Contact Person Name
- Marcel Tantau
- Contact Person Email
- mtantau@gmail.com
- Site Name
- Spitalul Clinic Colentina Bucuresti
- Department Name
- Gastroenterology
- Principal Investigator Name
- Radu Bogdan Mateescu
- Principal Investigator Email
- bogmateescu@gmail.com
- Contact Person Name
- Radu Bogdan Mateescu
- Contact Person Email
- bogmateescu@gmail.com
Poland
- Earliest CTIS Part Ii Submission Date
- 30-03-2026
- Latest Decision Or Authorization Date
- 30-04-2026
- Processing Time Days
- 31
- Number Of Sites
- 29
- Number Of Participants
- 51
Sites
- Site Name
- Etg Zamosc Sp. z o.o.
- Department Name
- ETG Zamość
- Principal Investigator Name
- Katarzyna Wójcik
- Principal Investigator Email
- k.wojcik@etg-network.com
- Contact Person Name
- Katarzyna Wójcik
- Contact Person Email
- k.wojcik@etg-network.com
- Site Name
- Futuremeds Sp. z o.o. (Wroclaw)
- Department Name
- FutureMeds Wrocław
- Principal Investigator Name
- Rafał Wierzbicki
- Principal Investigator Email
- Rafal.wierzbicki@futuremeds.com
- Contact Person Name
- Rafał Wierzbicki
- Contact Person Email
- Rafal.wierzbicki@futuremeds.com
- Site Name
- Medical Network Sp. z o.o.
- Department Name
- WIP Warsaw IBD Point Profesor Kierkuś
- Principal Investigator Name
- Jarosław Kierkuś
- Principal Investigator Email
- j.kierkus@med-net.pl
- Contact Person Name
- Jarosław Kierkuś
- Contact Person Email
- j.kierkus@med-net.pl
- Site Name
- Etg Warszawa Sp. z o.o.
- Department Name
- ETG Warszawa
- Principal Investigator Name
- Marek Bugajski
- Principal Investigator Email
- m.bugajski@etg-network.com
- Contact Person Name
- Marek Bugajski
- Contact Person Email
- m.bugajski@etg-network.com
- Site Name
- Medicome Sp. z o.o.
- Department Name
- Oświęcimskie Centrum Badań Klinicznych
- Principal Investigator Name
- Iwona Kobielusz- Gembala
- Principal Investigator Email
- iwonagembala@wp.pl
- Contact Person Name
- Iwona Kobielusz- Gembala
- Contact Person Email
- iwonagembala@wp.pl
- Site Name
- Futuremeds Sp. z o.o. (Warsaw)
- Department Name
- FutureMeds Warszawa Centrum
- Principal Investigator Name
- Alina Walczak
- Principal Investigator Email
- alina.walczak@futuremeds.com
- Contact Person Name
- Alina Walczak
- Contact Person Email
- alina.walczak@futuremeds.com
- Site Name
- Manermed Sp. z o.o.
- Department Name
- Centrum Medyczne "MEDIS"
- Principal Investigator Name
- Maria Kłopocka
- Principal Investigator Email
- mariaklopocka@cm-medis.pl
- Contact Person Name
- Maria Kłopocka
- Contact Person Email
- mariaklopocka@cm-medis.pl
- Site Name
- Synexus Polska Sp. z o.o. (Gdansk)
- Department Name
- Oddział w Gdańsku
- Principal Investigator Name
- Marek Cesarz
- Principal Investigator Email
- marek.cesarz@trialmed.com
- Contact Person Name
- Marek Cesarz
- Contact Person Email
- marek.cesarz@trialmed.com
- Site Name
- Samodzielny Publiczny Zaklad Opieki Zdrowotnej Uniwersytecki Szpital Kliniczny Nr 1 Im. Norberta Barlickiego Uniwersytetu Medycznego W Lodzi
- Department Name
- Oddział Kliniczny Gastroenterologii Ogólnej i Onkologicznej
- Principal Investigator Name
- Ewa Małecka-Wojciesko
- Principal Investigator Email
- ewa.malecka-panas@umed.lodz.pl
- Contact Person Name
- Ewa Małecka-Wojciesko
- Contact Person Email
- ewa.malecka-panas@umed.lodz.pl
- Site Name
- Therapia Nova Sp. z o.o.
- Department Name
- Therapia Nova
- Principal Investigator Name
- Jacek Wójtowicz
- Principal Investigator Email
- kontakt.therapianova@gmail.com
- Contact Person Name
- Jacek Wójtowicz
- Contact Person Email
- kontakt.therapianova@gmail.com
- Site Name
- Gastromed Sp. z o.o. (Torun)
- Principal Investigator Name
- Marcin Zmudziński
- Principal Investigator Email
- m.zmudek2@gmail.com
- Contact Person Name
- Marcin Zmudziński
- Contact Person Email
- m.zmudek2@gmail.com
- Site Name
- Osrodek Badan Klinicznych CLINSANTE S. C
- Principal Investigator Name
- Michał Walczak
- Principal Investigator Email
- michal.walczak@clinsante.pl
- Contact Person Name
- Michał Walczak
- Contact Person Email
- michal.walczak@clinsante.pl
- Site Name
- Centrum Medyczne Kermed Renata Bijata-Bronisz I Ewa Kowalinska Sp. j.
- Department Name
- NZOZ CENTRUM MEDYCZNE KERmed
- Principal Investigator Name
- Patryk Korga
- Principal Investigator Email
- patryk.korga@kermed.pl
- Contact Person Name
- Patryk Korga
- Contact Person Email
- patryk.korga@kermed.pl
- Site Name
- Centrum Medyczne Oporow
- Principal Investigator Name
- Radosław Kempiński
- Principal Investigator Email
- radoslaw.kempinski@cmoporow.com
- Contact Person Name
- Radosław Kempiński
- Contact Person Email
- radoslaw.kempinski@cmoporow.com
- Site Name
- Nowe Zdrowie-Ck Kieltucki I Wspolnicy Sp. j.
- Principal Investigator Name
- Jacek Kiełtucki
- Principal Investigator Email
- jacek.kieltucki@nowezdrowie-ck.pl
- Contact Person Name
- Jacek Kiełtucki
- Contact Person Email
- jacek.kieltucki@nowezdrowie-ck.pl
- Site Name
- Futuremeds Sp. z o.o. (Targówek)
- Department Name
- FutureMeds Targówek
- Principal Investigator Name
- Magda Fliszkiewicz
- Principal Investigator Email
- magda.fliszkiewicz@futuremeds.com
- Contact Person Name
- Magda Fliszkiewicz
- Contact Person Email
- magda.fliszkiewicz@futuremeds.com
- Site Name
- Synexus Polska Sp. z o.o. (Katowice)
- Department Name
- Oddział w Katowicach
- Principal Investigator Name
- Magdalena Olszanecka-Glinianowicz
- Principal Investigator Email
- magdalena.og@trailmed.com
- Contact Person Name
- Magdalena Olszanecka-Glinianowicz
- Contact Person Email
- magdalena.og@trailmed.com
- Site Name
- Wielkopolskie Centrum Medyczne Sp. z o.o.
- Department Name
- Szpital Św. Wojciecha; Poradania Gastroenterologiczna
- Principal Investigator Name
- Bartosz Cybułka
- Principal Investigator Email
- sekretariat@szpitalswwojciecha.pl
- Contact Person Name
- Bartosz Cybułka
- Contact Person Email
- sekretariat@szpitalswwojciecha.pl
- Site Name
- Zaniewski Bilski Sp. z o.o.
- Department Name
- Przychodnia Medicus filia w Olsztynie
- Principal Investigator Name
- Anna Woś- Zaniewska
- Principal Investigator Email
- kontakt@medicusolsztyn.pl
- Contact Person Name
- Anna Woś- Zaniewska
- Contact Person Email
- kontakt@medicusolsztyn.pl
- Site Name
- Futuremeds Sp. z o.o. (Krakow)
- Department Name
- FutureMeds Kraków
- Principal Investigator Name
- Ewelina Malec
- Principal Investigator Email
- ewelina.malec@futuremeds.com
- Contact Person Name
- Ewelina Malec
- Contact Person Email
- ewelina.malec@futuremeds.com
- Site Name
- Szpital Miejski Sw. Jana Pawla II W Elblagu
- Department Name
- Oddział Chorób Wewnętrznych
- Principal Investigator Name
- Krzysztof Niezgoda
- Principal Investigator Email
- sekretariat-wew@szpitalmiejski.elblag.pl
- Contact Person Name
- Krzysztof Niezgoda
- Contact Person Email
- sekretariat-wew@szpitalmiejski.elblag.pl
- Site Name
- Szpital Czerniakowski Sp. z o.o.
- Department Name
- Oddział Chorób Wewnętrznych
- Principal Investigator Name
- Kamil Wrzosek
- Principal Investigator Email
- kwrzosek07@gmail.com
- Contact Person Name
- Kamil Wrzosek
- Contact Person Email
- kwrzosek07@gmail.com
- Site Name
- Jst Sp. z o.o.
- Department Name
- Centrum Medyczne Klara
- Principal Investigator Name
- Zofia Jamrozik- Kruk
- Principal Investigator Email
- komorki@cm-klara.pl
- Contact Person Name
- Zofia Jamrozik- Kruk
- Contact Person Email
- komorki@cm-klara.pl
- Site Name
- Synexus Polska Sp. z o.o. (Poznan)
- Department Name
- Oddział w Poznaniu
- Principal Investigator Name
- Magdalena Andrzejewska
- Principal Investigator Email
- magdalena.andrzejewska@trailmed.com
- Contact Person Name
- Magdalena Andrzejewska
- Contact Person Email
- magdalena.andrzejewska@trailmed.com
- Site Name
- Samodzielny Publiczny Zaklad Opieki Zdrowotnej Szpital Uniwersytecki W Krakowie
- Department Name
- Zakład Endoskopii NSSU
- Principal Investigator Name
- Michał Kukla
- Principal Investigator Email
- mkukla@su.krakow.pl
- Contact Person Name
- Michał Kukla
- Contact Person Email
- mkukla@su.krakow.pl
- Site Name
- Vita Longa Sp. z o.o.
- Department Name
- NZOZ "Vita Longa" Sp. z o.o.
- Principal Investigator Name
- Przemysław Ramos
- Principal Investigator Email
- przemyslaw.ramos@researchsolutions.pl
- Contact Person Name
- Przemysław Ramos
- Contact Person Email
- przemyslaw.ramos@researchsolutions.pl
- Site Name
- Bonifraterskie Centrum Medyczne Sp. z o.o.
- Department Name
- Szpital Zakonu Bonifratrów św. Jana Bożego w Łodzi; Dział Endoskopii
- Principal Investigator Name
- Wojciech Piotrowski
- Principal Investigator Email
- wojtekp4@wp.pl
- Contact Person Name
- Wojciech Piotrowski
- Contact Person Email
- wojtekp4@wp.pl
- Site Name
- EMC Instytut Medyczny S.A.
- Department Name
- Prywatna Lecznica "Certus" Szpital Nr 1, Prywatna Lecznica Certus Ambulatoria
- Principal Investigator Name
- Piotr Szabłowski
- Principal Investigator Email
- szapi@mp.pl
- Contact Person Name
- Piotr Szabłowski
- Contact Person Email
- szapi@mp.pl
- Site Name
- Gastromed Kralisz Romatowski Stachurska Sp. j.
- Department Name
- NZOZ Specjalistyczne Centrum Gastrologii GASTROMED
- Principal Investigator Name
- Jacek Romatowski
- Principal Investigator Email
- biuro@gastromed.info
- Contact Person Name
- Jacek Romatowski
- Contact Person Email
- biuro@gastromed.info
Sponsor
Primary sponsor
- Full Name
- Cinclus Pharma Holding AB (publ)
- Organisation Type
- Pharmaceutical company
- Country Of Registered Address
- Sweden
Contract research organisations
- Name
- Psi Cro AG
- Responsibilities
- Feasibility, Medical Monitoring, Translations, Trial Supply Management, Vendor Management
Third parties
- {"country":"Switzerland","full_name":"Psi Cro AG","duties_or_roles":"Feasibility, Medical Monitoring, Translations, Trial Supply Management, Vendor Management (as listed in sponsor duties)","organisation_type":"Pharmaceutical company"}
Investigational products
- Investigational Product Name
- Linaprazan glurate
- Active Substance
- LINAPRAZAN GLURATE
- Modality
- Small molecule
- Routes Of Administration
- ORAL USE
- Route
- Oral
- Authorisation Status
- prodAuthStatus=1 (as listed in productDictionaryInfo)
- Dose Levels
- High dose and Low dose arms described (exact mg not specified in English content)
- Investigational Product Name
- LANSOPRAZOLE
- Active Substance
- LANSOPRAZOLE
- Modality
- Small molecule
- Routes Of Administration
- ORAL USE
- Route
- Oral
- Authorisation Status
- prodAuthStatus=2 (as listed in productDictionaryInfo)
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