Clinical trial • Phase I • Oncology|Gastroenterology|Immunology

Tolinapant (ASTX660) for Locally advanced rectal cancer

Phase I trial of Tolinapant (ASTX660) for Locally advanced rectal cancer. open-label. 78 participants.

Overview

Trial Therapeutic Area
Oncology|Gastroenterology|Immunology
Trial Disease
Locally advanced rectal cancer
Trial Stage
Phase I

Key dates

Initial CTIS Submission Date
16-04-2024
First CTIS Authorization Date
10-06-2024

Trial design

open-label Phase I trial across 2 sites in France.

Open Label
Yes
Target Sample Size
78

Recruitment

Planned Sample Size
78
Recruitment Window Months
98

Geography

Total Number Of Sites
2
Total Number Of Participants
78

France

Earliest CTIS Part Ii Submission Date
24-04-2024
Latest Decision Or Authorization Date
10-06-2024
Processing Time Days
47
Number Of Sites
2
Number Of Participants
78

Sites

Site Name
Centre Leon Berard
Department Name
ONCOLOGIE
Contact Person Name
Jessica SERRAND
Site Name
Institut Gustave Roussy
Department Name
ONCOLOGIE
Contact Person Name
Eric DEUTSCH
Contact Person Email
eric.deutsch@gustaveroussy.fr

Sponsor

Primary sponsor

Full Name
Institut Gustave Roussy
Organisation Type
Hospital/Clinic/Other health care facility
Country Of Registered Address
France

Investigational products

Investigational Product Name
Tolinapant (ASTX660)
Combination Treatment
Yes

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