Clinical trial • Phase I • Oncology
Tislelizumab for Advanced or metastatic solid tumors | Hepatocellular carcinoma | Squamous non-small cell lung cancer | Gastric cancer
Phase I trial of Tislelizumab for Advanced or metastatic solid tumors | Hepatocellular carcinoma | Squamous non-small cell lung cancer | Gastric cancer.
Overview
- Trial Therapeutic Area
- Oncology
- Trial Disease
- Advanced or metastatic solid tumors | Hepatocellular carcinoma | Squamous non-small cell lung cancer | Gastric cancer
- Trial Stage
- Phase I
- Drug Modality
- Monoclonal antibody | Other
Key dates
- Initial CTIS Submission Date
- 05-12-2025
- First CTIS Authorization Date
- 15-04-2026
Trial design
Phase I trial across 9 sites in France, Italy.
- Target Sample Size
- 229
Eligibility
Recruits 229 Vulnerable population not selected; no consent/assent information provided..
- Vulnerable Population
- Vulnerable population not selected; no consent/assent information provided.
Recruitment
- Planned Sample Size
- 229
- Recruitment Window Months
- 32
Geography
- Total Number Of Sites
- 9
- Total Number Of Participants
- 56
France
- Earliest CTIS Part Ii Submission Date
- 06-02-2026
- Latest Decision Or Authorization Date
- 15-04-2026
- Processing Time Days
- 68
- Number Of Sites
- 5
- Number Of Participants
- 39
Sites
- Site Name
- Centr Georges Francois Leclerc
- Department Name
- Oncologie Medicale
- Contact Person Name
- Francois Ghiringhelli
- Contact Person Email
- xxxxxx@xxxxxxx.fr
- Site Name
- Hopital Beaujon
- Department Name
- Unité Cancer du foie et innovation thérapeutique
- Contact Person Name
- Mohamed Bouattour
- Contact Person Email
- xxxxxx@xxxxxxx.fr
- Site Name
- Institut Regional Du Cancer De Montpellier
- Department Name
- Oncologie Medicale
- Contact Person Name
- Diego Tosi
- Contact Person Email
- xxxxxx@xxxxxxx.fr
- Site Name
- Institut Gustave Roussy
- Department Name
- Département d'innovation Thérapeutique et des Essais Précoces (DITEP)
- Contact Person Name
- Christophe Massard
- Contact Person Email
- xxxxxx@xxxxxxx.fr
- Site Name
- Centre Hospitalier Universitaire De Nantes
- Department Name
- Oncologie Medicale
- Contact Person Name
- Yann Touchefeu
- Contact Person Email
- xxxxxx@xxxxxxx.fr
Italy
- Earliest CTIS Part Ii Submission Date
- 13-03-2026
- Latest Decision Or Authorization Date
- 15-04-2026
- Processing Time Days
- 33
- Number Of Sites
- 4
- Number Of Participants
- 17
Sites
- Site Name
- IRCCS Istituto Nazionale Tumori Fondazione Pascale
- Department Name
- S.C. Sperimentazioni cliniche
- Contact Person Name
- Adriano Gravina
- Contact Person Email
- a.gravina@istitutotumori.na.it
- Site Name
- Humanitas Mirasole S.p.A.
- Department Name
- Operating Unit of Oncology and Hematology
- Contact Person Name
- Matteo Simonelli
- Contact Person Email
- matteosimonelli@cancercenter.humanitas.it
- Site Name
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
- Department Name
- Medical Oncology
- Contact Person Name
- Gennaro Daniele
- Contact Person Email
- gennaro.daniele@policlinogemelli.it
- Site Name
- Istituto Oncologico Veneto
- Department Name
- Medical Oncology 1 Unit
- Contact Person Name
- Sara Lonardi
- Contact Person Email
- sara.lonardi@iov.veneto.it
Sponsor
Primary sponsor
- Full Name
- BeOne Medicines AG
- Organisation Type
- Pharmaceutical company
- Country Of Registered Address
- Switzerland
Investigational products
- Investigational Product Name
- BGB-B2033
- Investigational Product Name
- Tislelizumab
- Active Substance
- Tislelizumab
- Modality
- Monoclonal antibody
- Investigational Product Name
- Bevacizumab
- Active Substance
- Bevacizumab
- Modality
- Monoclonal antibody
- Combination Treatment
- Yes
Related trials
Other published trials that may interest you.
- GDC-9545 for Locally advanced or metastatic estrogen receptor-positive breast cancer
- Abemaciclib for Stage IV lung cancer | Breast cancer
- BGB-43395 for Advanced or metastatic solid tumors | Hormone receptor positive HER2 negative breast cancer
- AZD9833 for Estrogen receptor-positive HER2-negative advanced breast cancer
- Pembrolizumab for Classical Hodgkin lymphoma | Melanoma | Solid tumours (MSI-H/dMMR) | Solid tumours (TMB-H)