Clinical trial • Phase I • Neurology
RO7121932 for Multiple sclerosis
Phase I trial of RO7121932 for Multiple sclerosis. None/Not specified-controlled. 20 participants.
Overview
- Trial Therapeutic Area
- Neurology
- Trial Disease
- Multiple sclerosis
- Trial Stage
- Phase I
Key dates
- Initial CTIS Submission Date
- 22-02-2024
- First CTIS Authorization Date
- 15-03-2024
Trial design
None/Not specified-controlled Phase I trial across 18 sites in Italy, Belgium, Portugal and others.
- Comparator
- None/Not specified
- Target Sample Size
- 20
Eligibility
Recruits 20 Vulnerable population selected; no further details on the nature of vulnerability or consent/assent procedures available in the provided source..
- Vulnerable Population
- Vulnerable population selected; no further details on the nature of vulnerability or consent/assent procedures available in the provided source.
Recruitment
- Planned Sample Size
- 20
- Recruitment Window Months
- 43
Geography
- Total Number Of Sites
- 18
- Total Number Of Participants
- 55
Italy
- Latest Decision Or Authorization Date
- 08-01-2026
- Number Of Sites
- 2
- Number Of Participants
- 3
Sites
- Site Name
- Ospedale San Raffaele S.r.l.
- Department Name
- Neurologia Neurofisiologia Neuroriabilitazione-Centro Sclerosi Multipla
- Contact Person Name
- Massimo Filippi
- Contact Person Email
- filippi.massimo@hsr.it
- Site Name
- IRCCS Foundation Istituto Neurologico Carlo Besta
- Department Name
- U.O.C. Neurologia IV - Neuroimmunologia e Malattie Neuromuscolari
- Contact Person Name
- Laura Brambilla
- Contact Person Email
- laura.brambilla@istituto-besta.it
Belgium
- Latest Decision Or Authorization Date
- 07-01-2026
- Number Of Sites
- 2
- Number Of Participants
- 9
Sites
- Site Name
- Universitair Ziekenhuis Gent
- Department Name
- Neurology
- Contact Person Name
- Guy Laureys
- Contact Person Email
- Guy.Laureys@uzgent.be
- Site Name
- Cliniques Universitaires Saint-Luc
- Department Name
- Neurology
- Contact Person Name
- Vincent Van Pesch
- Contact Person Email
- vincent.vanpesch@saintluc.uclouvain.be
Portugal
- Latest Decision Or Authorization Date
- 12-01-2026
- Number Of Sites
- 3
- Number Of Participants
- 6
Sites
- Site Name
- CCAB Centro Clinico Academico Braga Associacao
- Department Name
- Neurologia
- Contact Person Name
- João Cerqueira
- Contact Person Email
- 2ca@ccabraga.org
- Site Name
- Unidade Local De Saude De Entre O Douro E Vouga E.P.E.
- Department Name
- Serviço de Neurologia
- Contact Person Name
- Luís Ruano
- Contact Person Email
- alice.coelho@chedv.min-saude.pt
- Site Name
- Unidade Local De Saude De Sao Jose E.P.E.
- Department Name
- Centro de Responsabilidade Integrada de Esclerose Múltipla
- Contact Person Name
- João Sequeira
- Contact Person Email
- ensaiosclinicos@ulssjose.min-saude.pt
Romania
- Latest Decision Or Authorization Date
- 13-01-2026
- Number Of Sites
- 2
- Number Of Participants
- 13
Sites
- Site Name
- Arensia Clinics S.R.L.
- Department Name
- Neurology
- Contact Person Name
- Adina Maria Roceanu
- Contact Person Email
- contact-ro@arensia-em.com
- Site Name
- Spitalul Clinic Judetean De Urgenta Cluj
- Department Name
- Neurology
- Contact Person Name
- Vitalie Vacaras
- Contact Person Email
- secretariat@scjucluj.ro
Poland
- Latest Decision Or Authorization Date
- 09-01-2026
- Number Of Sites
- 3
- Number Of Participants
- 10
Sites
- Site Name
- Samodzielny Publiczny Szpital Kliniczny Nr 1 Im.Prof.Stanislawa Szyszko Slaskiego Uniwersytetu Medycznego W Katowicach
- Department Name
- Oddział Neurologiczny
- Contact Person Name
- Monika Adamczyk-Sowa
- Contact Person Email
- neurologia@szpital.zabrze.pl
- Site Name
- Euromedis Sp. z o.o.
- Department Name
- Centrum Medyczne EUROMEDIS
- Contact Person Name
- Marcin Ratajczak
- Contact Person Email
- rejestracjabk@euromedis.pl
- Site Name
- Med Polonia Sp. z o.o.
- Contact Person Name
- Karolina Piasecka - Stryczyńska
- Contact Person Email
- agnieszka.kotlinska@medpolonia.com.pl
Germany
- Latest Decision Or Authorization Date
- 08-01-2026
- Number Of Sites
- 5
- Number Of Participants
- 12
Sites
- Site Name
- Universitaetsklinikum Ulm AöR
- Department Name
- Dept. of Neurology
- Contact Person Name
- Hayrettin Tumani
- Contact Person Email
- hayrettin.tumani@uni-ulm.de
- Site Name
- Universitaetsklinikum Muenster AöR
- Department Name
- Klinik u. Poliklinik f. Neurologie
- Contact Person Name
- Luisa Klotz
- Contact Person Email
- luisa.klotz@ukmuenster.de
- Site Name
- Universitaetsklinikum Tuebingen AöR
- Department Name
- Dept. of Neurology
- Contact Person Name
- Markus Kowarik
- Contact Person Email
- markus.kowarik@med.uni-tuebingen.de
- Site Name
- Klinikum rechts der Isar der TU Muenchen AöR
- Department Name
- Neurologische Klinik und Poliklinik im Neuro-Kopf-Zentrum
- Contact Person Name
- Achim Berthele
- Contact Person Email
- achim.berthele@mri.tum.de
- Site Name
- Universitaetsklinikum Carl Gustav Carus Dresden an der Technischen Universitaet Dresden AöR
- Department Name
- MS Center Dresden
- Contact Person Name
- Tjalf Ziemssen
- Contact Person Email
- Tjalf.Ziemssen@ukdd.de
Spain
- Latest Decision Or Authorization Date
- 07-05-2026
- Number Of Sites
- 1
- Number Of Participants
- 2
Sites
- Site Name
- Hospital Universitari Vall D Hebron
- Department Name
- Neurology
- Contact Person Name
- Mar Tintore Subirana
- Contact Person Email
- mtintore@cem-cat.org
Sponsor
Primary sponsor
- Full Name
- F. Hoffmann-La Roche AG
- Organisation Type
- Pharmaceutical company
- Country Of Registered Address
- Switzerland
Investigational products
- Investigational Product Name
- RO7121932
- Routes Of Administration
- Intravenous and Subcutaneous
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