Clinical trial • Phase I • Haematology

multi-peptide(s) and XS15 (TLR1/2 ligand) for Acute myeloid leukemia

Phase I trial of multi-peptide(s) and XS15 (TLR1/2 ligand) for Acute myeloid leukemia. None/Not specified-controlled. 20 participants.

Overview

Trial Therapeutic Area
Haematology
Trial Disease
Acute myeloid leukemia
Trial Stage
Phase I
Drug Modality
Vaccine|Peptide/protein/enzyme|Small molecule

Key dates

Initial CTIS Submission Date
31-01-2024
First CTIS Authorization Date
18-04-2024

Trial design

None/Not specified-controlled Phase I trial across 1 site in Germany.

Comparator
None/Not specified
Target Sample Size
20

Eligibility

Recruits 20 Vulnerable population not selected; no specific consent/assent handling mentioned..

Vulnerable Population
Vulnerable population not selected; no specific consent/assent handling mentioned.

Recruitment

Planned Sample Size
20
Recruitment Window Months
23

Geography

Total Number Of Sites
1
Total Number Of Participants
20

Germany

Earliest CTIS Part Ii Submission Date
27-03-2024
Latest Decision Or Authorization Date
18-04-2024
Processing Time Days
22
Number Of Sites
1
Number Of Participants
20

Sites

Site Name
Universitaetsklinikum Tuebingen AöR
Department Name
KKE Translationale Immunologie
Contact Person Name
Helmut Salih
Contact Person Email
kketi@med.uni-tuebingen.de
Number Of Participants
20

Sponsor

Primary sponsor

Full Name
Universitaetsklinikum Tuebingen AöR
Organisation Type
Hospital/Clinic/Other health care facility
Country Of Registered Address
Germany

Investigational products

Investigational Product Name
Multi-peptide vaccination adjuvanted with the TLR1/2 ligand XS15
Active Substance
multi-peptide(s) and XS15 (TLR1/2 ligand)
Modality
Vaccine|Peptide/protein/enzyme|Small molecule
Combination Treatment
Yes

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