Clinical trial • Phase I • Neurology

MTX46943 for Alzheimer's disease

Phase I trial of MTX46943 for Alzheimer's disease. 123 participants.

Overview

Trial Therapeutic Area
Neurology
Trial Disease
Alzheimer's disease
Trial Stage
Phase I

Key dates

Initial CTIS Submission Date
14-07-2025
First CTIS Authorization Date
04-09-2025

Trial design

Phase I trial across 1 site in Netherlands.

Single Multiple Or Escalation Dose Combined
Yes
Target Sample Size
123

Eligibility

Recruits 123 Vulnerable population selected; no further details on the type of vulnerable population, or on consent/assent handling, are provided in the CTIS record..

Vulnerable Population
Vulnerable population selected; no further details on the type of vulnerable population, or on consent/assent handling, are provided in the CTIS record.

Recruitment

Planned Sample Size
123
Recruitment Window Months
10

Geography

Total Number Of Sites
1
Total Number Of Participants
123

Netherlands

Earliest CTIS Part Ii Submission Date
04-09-2025
Latest Decision Or Authorization Date
26-02-2026
Processing Time Days
175
Number Of Sites
1
Number Of Participants
123

Sites

Site Name
Pharmaceutical Research Associates Group B.V.
Department Name
Program Management
Contact Person Name
Maria Velinova
Contact Person Email
maria.velinova@iconplc.com

Sponsor

Primary sponsor

Full Name
Muna Therapeutics ApS
Organisation Type
Pharmaceutical company
Country Of Registered Address
Denmark

Contract research organisations

Name
Pharmaceutical Research Associates Group B.V.
Responsibilities
Listed in trialSites as site/program management contact (department: Program Management); contact person Maria Velinova (email: maria.velinova@iconplc.com).

Investigational products

Investigational Product Name
MTX46943

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