Clinical trial • Phase I • Rare Disease|Nephrology

MR-L45 for Autosomal dominant polycystic kidney disease

Phase I trial of MR-L45 for Autosomal dominant polycystic kidney disease. 72 participants.

Overview

Trial Therapeutic Area
Rare Disease|Nephrology
Trial Disease
Autosomal dominant polycystic kidney disease
Trial Stage
Phase I

Key dates

Initial CTIS Submission Date
20-02-2026
First CTIS Authorization Date
01-04-2026

Trial design

Phase I trial across 1 site in Netherlands.

Target Sample Size
72

Eligibility

Recruits 72 Vulnerable population selected (isVulnerablePopulationSelected = true); no further details on consent or assent provided..

Vulnerable Population
Vulnerable population selected (isVulnerablePopulationSelected = true); no further details on consent or assent provided.

Recruitment

Planned Sample Size
72
Recruitment Window Months
12

Geography

Total Number Of Sites
1
Total Number Of Participants
72

Netherlands

Earliest CTIS Part Ii Submission Date
31-03-2026
Latest Decision Or Authorization Date
01-04-2026
Processing Time Days
1
Number Of Sites
1
Number Of Participants
72

Sites

Site Name
Van Swietenlaan 6
Department Name
Program Management
Contact Person Name
Renger Tiessen
Contact Person Email
Renger.Tiessen@iconplc.com

Sponsor

Primary sponsor

Full Name
Mironid Limited
Organisation Type
Pharmaceutical company
Country Of Registered Address
United Kingdom

Contract research organisations

Name
Pharmaceutical Research Associates Group B.V.
Responsibilities
Program Management; site contact (email Renger.Tiessen@iconplc.com)

Investigational products

Investigational Product Name
MR-L45
First In Human
Yes

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