Clinical trial • Not applicable • Other

METHYLPREDNISOLONE HEMISUCCINATE for Postoperative sequelae

Not applicable trial of METHYLPREDNISOLONE HEMISUCCINATE for Postoperative sequelae.

Overview

Trial Therapeutic Area
Other
Trial Disease
Postoperative sequelae
Trial Stage
Not applicable
Drug Modality
Small molecule

Key dates

Initial CTIS Submission Date
08-01-2025
First CTIS Authorization Date
15-01-2025

Trial design

Randomised, intervention: solu-medrol (methylprednisolone hemisuccinate) preoperative intramasseteric/intramuscular injection (dose/schedule not specified); comparator: placebo (dose and schedule not specified)-controlled Not applicable trial across 1 site in Hungary.

Randomised
Yes
Comparator
Intervention: SOLU-MEDROL (methylprednisolone hemisuccinate) preoperative intramasseteric/intramuscular injection (dose/schedule not specified); Comparator: Placebo (dose and schedule not specified)
Target Sample Size
30

Eligibility

Recruits 30 adults.

Inclusion criteria

  • {"criterion_text":"- on both sides existing lower wisdom teeth, in deeper impaction and similar position\n- between the age of 18 and 50\n- healthy\n- not receiving any medication that can affect the treatment\n- good oral hygiene"}

Exclusion criteria

  • {"criterion_text":"- smoking\n- poor oral hygiene\n- receiving medication that can affect the treatment\n- disease or general state that can affect the treatment\n- symptoms of inflammation in the surgical area\n- if the patient can not appear on the control examinations"}

Endpoints

Primary endpoints

  • {"endpoint_text":"- -","definition_or_measurement_approach":""}

Recruitment

Planned Sample Size
30
Recruitment Window Months
23

Geography

Total Number Of Sites
1
Total Number Of Participants
30

Hungary

Earliest CTIS Part Ii Submission Date
08-01-2025
Latest Decision Or Authorization Date
15-01-2025
Processing Time Days
7
Number Of Sites
1
Number Of Participants
30

Sites

Site Name
Semmelweis University
Department Name
Oro-Maxillofacial Surgery
Contact Person Name
Árpád Joób-Fancsaly
Number Of Participants
30

Sponsor

Primary sponsor

Full Name
Semmelweis University
Organisation Type
Educational Institution
Country Of Registered Address
Hungary

Investigational products

Investigational Product Name
SOLU-MEDROL 40 mg/1 mL, poudre et solvant pour solution injectable
Active Substance
METHYLPREDNISOLONE HEMISUCCINATE
Modality
Small molecule
Routes Of Administration
SOLUTION FOR INJECTION
Route
SOLUTION FOR INJECTION
Authorisation Status
Authorised (marketing authorisation available; authorisation country: FR)
Maximum Dose
1000 mg

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