Clinical trial • Phase III • Immunology

Methotrexate for Rheumatoid arthritis

Phase III trial of Methotrexate for Rheumatoid arthritis. 16 participants.

Overview

Trial Therapeutic Area
Immunology
Trial Disease
Rheumatoid arthritis
Trial Stage
Phase III
Drug Modality
Small molecule|Small molecule

Key dates

Initial CTIS Submission Date
07-07-2025
First CTIS Authorization Date
19-08-2025

Trial design

Phase III trial across 1 site in Netherlands.

Target Sample Size
16
Trial Duration For Participant
225

Eligibility

Recruits 16 No vulnerable population selected; no additional consent/assent information provided..

Vulnerable Population
No vulnerable population selected; no additional consent/assent information provided.

Recruitment

Planned Sample Size
16
Recruitment Window Months
7

Geography

Total Number Of Sites
1
Total Number Of Participants
16

Netherlands

Earliest CTIS Part Ii Submission Date
15-08-2025
Latest Decision Or Authorization Date
24-04-2026
Processing Time Days
252
Number Of Sites
1
Number Of Participants
16

Sites

Site Name
Centre for Human Drug Research
Department Name
Internal Medicine
Principal Investigator Name
Naomi Klarenbeek
Principal Investigator Email
clintrials@chdr.nl
Contact Person Name
Naomi Klarenbeek
Contact Person Email
clintrials@chdr.nl
Number Of Participants
16

Sponsor

Primary sponsor

Full Name
Amplio Pharma B.V.
Organisation Type
Pharmaceutical company
Country Of Registered Address
Netherlands

Investigational products

Investigational Product Name
Methotrexate
Active Substance
Methotrexate
Modality
Small molecule
Investigational Product Name
Novobiocin
Active Substance
Novobiocin
Modality
Small molecule
Combination Treatment
Yes

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