Clinical trial • Phase I • Neurology
ION464 for Multiple system atrophy
Phase I trial of ION464 for Multiple system atrophy. 65 participants.
Overview
- Trial Therapeutic Area
- Neurology
- Trial Disease
- Multiple system atrophy
- Trial Stage
- Phase I
Key dates
- Initial CTIS Submission Date
- 04-07-2024
- First CTIS Authorization Date
- 14-08-2024
Trial design
Phase I trial across 11 sites in Germany, Portugal, Austria and others.
- Target Sample Size
- 65
Recruitment
- Planned Sample Size
- 65
- Recruitment Window Months
- 108
Geography
- Total Number Of Sites
- 11
- Total Number Of Participants
- 65
Germany
- Earliest CTIS Part Ii Submission Date
- 22-07-2024
- Latest Decision Or Authorization Date
- 26-11-2025
- Processing Time Days
- 492
- Number Of Sites
- 6
- Number Of Participants
- 20
Sites
- Site Name
- Philipps-Universitaet Marburg
- Department Name
- Neurology
- Principal Investigator Name
- Karla Eggert
- Principal Investigator Email
- eggert@med.uni-marburg.de
- Contact Person Name
- Karla Eggert
- Contact Person Email
- eggert@med.uni-marburg.de
- Site Name
- Klinikum der Universitaet Muenchen AöR
- Department Name
- Neurology
- Principal Investigator Name
- Guenter Hoeglinger
- Principal Investigator Email
- Guenter.Hoeglinger@med.uni-muenchen.de
- Contact Person Name
- Guenter Hoeglinger
- Contact Person Email
- Guenter.Hoeglinger@med.uni-muenchen.de
- Site Name
- Universitaetsklinikum Duesseldorf AöR
- Department Name
- Neurology
- Principal Investigator Name
- Alfons Schnitzler
- Principal Investigator Email
- schnitza@med.uni-duesseldorf.de
- Contact Person Name
- Alfons Schnitzler
- Contact Person Email
- schnitza@med.uni-duesseldorf.de
- Site Name
- Universitaetsmedizin Goettingen
- Department Name
- Neurology
- Principal Investigator Name
- Christoph van Riesen
- Principal Investigator Email
- christoph.van-riesen@med.uni-goettingen.de
- Contact Person Name
- Christoph van Riesen
- Contact Person Email
- christoph.van-riesen@med.uni-goettingen.de
- Site Name
- Universitaetsklinikum Ulm AöR
- Department Name
- Neurology
- Principal Investigator Name
- Georg Bernhard Landwehrmeyer
- Principal Investigator Email
- bernhard.landwehrmeyer@uni-ulm.de
- Contact Person Name
- Georg Bernhard Landwehrmeyer
- Contact Person Email
- bernhard.landwehrmeyer@uni-ulm.de
- Site Name
- Medizinische Hochschule Hannover
- Department Name
- Neurology
- Principal Investigator Name
- Guenter Hoeglinger
- Principal Investigator Email
- Hoeglinger.Guenter@mh-hannover.de
- Contact Person Name
- Guenter Hoeglinger
- Contact Person Email
- Hoeglinger.Guenter@mh-hannover.de
Portugal
- Earliest CTIS Part Ii Submission Date
- 22-07-2024
- Latest Decision Or Authorization Date
- 25-11-2025
- Processing Time Days
- 491
- Number Of Sites
- 1
- Number Of Participants
- 12
Sites
- Site Name
- Hospital De Loures EPE
- Department Name
- Neurology
- Principal Investigator Name
- Rita Simões
- Principal Investigator Email
- rita.simoes@hbeatrizangelo.pt
- Contact Person Name
- Rita Simões
- Contact Person Email
- rita.simoes@hbeatrizangelo.pt
Austria
- Earliest CTIS Part Ii Submission Date
- 22-07-2024
- Latest Decision Or Authorization Date
- 01-12-2025
- Processing Time Days
- 497
- Number Of Sites
- 1
- Number Of Participants
- 15
Sites
- Site Name
- Medizinische Universitaet Innsbruck
- Department Name
- Neurology
- Principal Investigator Name
- Florian Krismer
- Principal Investigator Email
- mui-oversight@i-med.ac.at
- Contact Person Name
- Florian Krismer
- Contact Person Email
- mui-oversight@i-med.ac.at
France
- Earliest CTIS Part Ii Submission Date
- 22-07-2024
- Latest Decision Or Authorization Date
- 28-01-2026
- Processing Time Days
- 555
- Number Of Sites
- 3
- Number Of Participants
- 18
Sites
- Site Name
- Assistance Publique Hopitaux De Paris
- Department Name
- Neurology
- Principal Investigator Name
- Jean-Christophe CORVOL
- Principal Investigator Email
- jean-christophe.corvol@aphp.fr
- Contact Person Name
- Jean-Christophe CORVOL
- Contact Person Email
- jean-christophe.corvol@aphp.fr
- Site Name
- Centre Hospitalier Universitaire De Toulouse
- Department Name
- Neurology
- Principal Investigator Name
- Olivier RASCOL
- Principal Investigator Email
- rascol@cict.fr
- Contact Person Name
- Olivier RASCOL
- Contact Person Email
- rascol@cict.fr
- Site Name
- Hospices Civils De Lyon
- Department Name
- Neurology
- Principal Investigator Name
- Stéphane THOBOIS
- Principal Investigator Email
- stephane.thobois@chu-lyon.fr
- Contact Person Name
- Stéphane THOBOIS
- Contact Person Email
- stephane.thobois@chu-lyon.fr
Sponsor
Primary sponsor
- Full Name
- Ionis Pharmaceuticals Inc.
- Organisation Type
- Pharmaceutical company
- Country Of Registered Address
- United States
Investigational products
- Investigational Product Name
- ION464
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