Clinical trial • Phase I/II • Immunology|Haematology|Oncology

Human T lymphoid progenitor cells (HTLP) for Hematologic malignancies|Acute myeloid leukemia

Phase I/II trial of Human T lymphoid progenitor cells (HTLP) for Hematologic malignancies|Acute myeloid leukemia. 10 participants.

Overview

Trial Therapeutic Area
Immunology|Haematology|Oncology
Trial Disease
Hematologic malignancies|Acute myeloid leukemia
Trial Stage
Phase I/II
Drug Modality
Cell therapy

Key dates

Initial CTIS Submission Date
22-07-2024
First CTIS Authorization Date
20-08-2024

Trial design

Phase I/II trial across 5 sites in France.

Target Sample Size
10
Trial Duration For Participant
2007

Eligibility

Recruits 10 No vulnerable population selected; trial includes adult patients only (isVulnerablePopulationSelected: false); no details provided on assent or special consent procedures..

Vulnerable Population
No vulnerable population selected; trial includes adult patients only (isVulnerablePopulationSelected: false); no details provided on assent or special consent procedures.

Recruitment

Planned Sample Size
10
Recruitment Window Months
66
Consent Approach
No detailed consent approach provided. Trial includes adult patients; informed consent is implied to be provided by participants themselves. isVulnerablePopulationSelected: false. No information on assent or languages.

Geography

Total Number Of Sites
5
Total Number Of Participants
10

France

Earliest CTIS Part Ii Submission Date
17-07-2024
Latest Decision Or Authorization Date
11-07-2025
Processing Time Days
359
Number Of Sites
5
Number Of Participants
10

Sites

Site Name
Assistance Publique Hopitaux De Paris
Department Name
75
Principal Investigator Name
OLIVIER HERMINE
Principal Investigator Email
olivier.hermine@aphp.fr
Contact Person Name
OLIVIER HERMINE
Contact Person Email
olivier.hermine@aphp.fr
Site Name
Institut Gustave Roussy
Department Name
94
Principal Investigator Name
Jean-Henri BOURHIS
Principal Investigator Email
jean-henri.bourhis@gustaveroussy.fr
Contact Person Name
Jean-Henri BOURHIS
Site Name
Assistance Publique Hopitaux De Paris
Department Name
75
Principal Investigator Name
NICOLAS BOISSEL
Principal Investigator Email
nicolas.boissel@aphp.fr
Contact Person Name
NICOLAS BOISSEL
Contact Person Email
nicolas.boissel@aphp.fr
Site Name
CHU De Bordeaux
Department Name
33
Principal Investigator Name
Edouard FORCADE
Principal Investigator Email
edouard.forcade@chu-bordeaux.fr
Contact Person Name
Edouard FORCADE
Site Name
Centre Hospitalier Universitaire De Toulouse
Department Name
31
Principal Investigator Name
Anne HUYNH
Principal Investigator Email
huynh.anne@iuct-oncopole.fr
Contact Person Name
Anne HUYNH
Contact Person Email
huynh.anne@iuct-oncopole.fr

Sponsor

Primary sponsor

Full Name
Assistance Publique Hopitaux De Paris
Organisation Type
Hospital/Clinic/Other health care facility
Country Of Registered Address
France

Investigational products

Investigational Product Name
Human T Lymphoid Progenitor (HTLP) injection
Active Substance
Human T lymphoid progenitor cells (HTLP)
Modality
Cell therapy
Routes Of Administration
Injection
Route
Injection

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