Clinical trial • Phase I • Oncology

Ectonucleotide pyrophosphatase/phosphodiesterase family member 3 antibody drug conjugate for Advanced solid tumors

Phase I trial of Ectonucleotide pyrophosphatase/phosphodiesterase family member 3 antibody drug conjugate for Advanced solid tumors. 240 participants.

Overview

Trial Therapeutic Area
Oncology
Trial Disease
Advanced solid tumors
Trial Stage
Phase I
Drug Modality
ADC

Key dates

Initial CTIS Submission Date
04-09-2025
First CTIS Authorization Date
21-11-2025

Trial design

Phase I trial across 2 sites in France.

Target Sample Size
240

Recruitment

Planned Sample Size
240
Recruitment Window Months
55

Geography

Total Number Of Sites
2
Total Number Of Participants
240

France

Earliest CTIS Part Ii Submission Date
05-11-2025
Latest Decision Or Authorization Date
12-03-2026
Processing Time Days
127
Number Of Sites
2
Number Of Participants
120

Sites

Site Name
Institut Gustave Roussy
Department Name
Drug Development Department (DITEP)
Principal Investigator Name
Anas GAZZAH
Principal Investigator Email
anas.gazzah@gustaveroussy.fr
Contact Person Name
Anas GAZZAH
Contact Person Email
anas.gazzah@gustaveroussy.fr
Site Name
Centre Leon Berard
Department Name
Department of medical oncology
Principal Investigator Name
Armelle VINCENEUX
Principal Investigator Email
armelle.vinceneux@lyon.unicancer.fr
Contact Person Name
Armelle VINCENEUX

Sponsor

Primary sponsor

Full Name
Janssen Cilag International
Organisation Type
Pharmaceutical company
Country Of Registered Address
Belgium

Investigational products

Investigational Product Name
JNJ-89862175
Active Substance
Ectonucleotide pyrophosphatase/phosphodiesterase family member 3 antibody drug conjugate
Modality
ADC

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