Clinical trial • Phase I • Infectious Disease
DF-006 for Chronic Hepatitis B
Phase I trial of DF-006 for Chronic Hepatitis B. Randomised, placebo (dose/schedule not specified)-controlled. 107 participants.
Overview
- Trial Therapeutic Area
- Infectious Disease
- Trial Disease
- Chronic Hepatitis B
- Trial Stage
- Phase I
- Drug Modality
- Small molecule
Key dates
- Initial CTIS Submission Date
- 05-12-2023
- First CTIS Authorization Date
- 16-04-2024
Trial design
Randomised, placebo (dose/schedule not specified)-controlled Phase I trial across 2 sites in Romania, Bulgaria.
- Randomised
- Yes
- Comparator
- Placebo (dose/schedule not specified)
- Single Multiple Or Escalation Dose Combined
- Yes
- Target Sample Size
- 107
Recruitment
- Planned Sample Size
- 107
- Recruitment Window Months
- 7
Geography
- Total Number Of Sites
- 2
- Total Number Of Participants
- 12
Romania
- Earliest CTIS Part Ii Submission Date
- 14-03-2024
- Latest Decision Or Authorization Date
- 16-04-2024
- Processing Time Days
- 33
- Number Of Sites
- 1
- Number Of Participants
- 7
Sites
- Site Name
- Spitalul Clinic Judetean De Urgenta Cluj
- Department Name
- Ophthalmology Building, 1st floor, wards 33, 34, and 35
- Contact Person Name
- Adriana Bintintan
- Contact Person Email
- abintintan@yahoo.com
- Number Of Participants
- 7
Bulgaria
- Earliest CTIS Part Ii Submission Date
- 03-04-2024
- Latest Decision Or Authorization Date
- 17-04-2024
- Processing Time Days
- 14
- Number Of Sites
- 1
- Number Of Participants
- 5
Sites
- Site Name
- Multiprofile Hospital for Active Treatment Sveta Sofia
- Department Name
- Internal Medicine
- Contact Person Name
- Vesselin Koltchakov
- Contact Person Email
- vesselin.koltchakov.ext@arensia-em.com
- Number Of Participants
- 5
Sponsor
Primary sponsor
- Full Name
- Zhejiang Yaoyuan Biotechnology Co. Ltd.
- Organisation Type
- Pharmaceutical company
- Country Of Registered Address
- China
Investigational products
- Investigational Product Name
- DF-006
- Modality
- Small molecule
- Routes Of Administration
- Oral
- Route
- oral
- First In Human
- Yes
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