Clinical trial • Phase I • Infectious Disease

Conditioned medium from a co-culture of M2-macrophages and fat-derived mesenchymal cells for Acute respiratory distress syndrome (ARDS) | SARS-CoV-2 infection | Influenza A infection | Influenza B infection | Respiratory syncytial virus (RSV) infection

Phase I trial of Conditioned medium from a co-culture of M2-macrophages and fat-derived mesenchymal cells for Acute respiratory distress syndrome (ARDS) |…

Overview

Trial Therapeutic Area
Infectious Disease
Trial Disease
Acute respiratory distress syndrome (ARDS) | SARS-CoV-2 infection | Influenza A infection | Influenza B infection | Respiratory syncytial virus (RSV) infection
Trial Stage
Phase I
Drug Modality
Other

Key dates

Initial CTIS Submission Date
12-10-2023
First CTIS Authorization Date
22-01-2024

Trial design

Randomised, placebo control (placebo), dose and schedule not specified Phase I trial across 3 sites in Spain.

Randomised
Yes
Comparator
Placebo control (placebo), dose and schedule not specified
Target Sample Size
50

Eligibility

Recruits 50 Vulnerable population selected (isVulnerablePopulationSelected = true); no details on consent or assent handling are provided in the record..

Vulnerable Population
Vulnerable population selected (isVulnerablePopulationSelected = true); no details on consent or assent handling are provided in the record.

Recruitment

Planned Sample Size
50
Recruitment Window Months
41

Geography

Total Number Of Sites
3
Total Number Of Participants
50

Spain

Earliest CTIS Part Ii Submission Date
30-08-2023
Latest Decision Or Authorization Date
13-05-2026
Processing Time Days
987
Number Of Sites
3
Number Of Participants
50

Sites

Site Name
Hospital Universitario De Fuenlabrada
Department Name
Medicina Interna
Principal Investigator Name
David Bernal Bello
Principal Investigator Email
david.bernal@salud.madrid.org
Contact Person Name
David Bernal Bello
Contact Person Email
david.bernal@salud.madrid.org
Site Name
Hospital Universitario Reina Sofia
Department Name
Servicio Enfermedades Infecciosas
Principal Investigator Name
Ángela María Cano Yuste
Principal Investigator Email
cayuam@hotmail.com
Contact Person Name
Ángela María Cano Yuste
Contact Person Email
cayuam@hotmail.com
Site Name
Hospital Universitario Principe De Asturias
Department Name
Medicina Interna
Principal Investigator Name
José Sanz Moreno
Principal Investigator Email
jsmoreno@salud.madrid.org
Contact Person Name
José Sanz Moreno
Contact Person Email
jsmoreno@salud.madrid.org

Sponsor

Primary sponsor

Full Name
Peaches Biotech S.L.
Organisation Type
Hospital/Clinic/Other health care facility
Country Of Registered Address
Spain

Investigational products

Investigational Product Name
PRS CK STORM
Active Substance
Conditioned medium from a co-culture of M2-macrophages and fat-derived mesenchymal cells
Modality
Other

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