Clinical trial • Phase I • Infectious Disease

BNT351 for HIV-1 infection

Phase I trial of BNT351 for HIV-1 infection. None/Not specified-controlled. 55 participants.

Overview

Trial Therapeutic Area
Infectious Disease
Trial Disease
HIV-1 infection
Trial Stage
Phase I
Drug Modality
Monoclonal antibody

Key dates

Initial CTIS Submission Date
10-10-2025
First CTIS Authorization Date
22-12-2025

Trial design

None/Not specified-controlled Phase I trial across 2 sites in Germany.

Comparator
None/Not specified
Target Sample Size
55

Eligibility

Recruits 55 Vulnerable population selected (isVulnerablePopulationSelected: true); no details on consent or assent handling available in the source..

Vulnerable Population
Vulnerable population selected (isVulnerablePopulationSelected: true); no details on consent or assent handling available in the source.

Recruitment

Planned Sample Size
55
Recruitment Window Months
15
Consent Approach
Not specified in the source

Geography

Total Number Of Sites
2
Total Number Of Participants
55

Germany

Earliest CTIS Part Ii Submission Date
11-12-2025
Latest Decision Or Authorization Date
20-01-2026
Processing Time Days
40
Number Of Sites
2
Number Of Participants
55

Sites

Site Name
Universitaetsklinikum Koeln AöR
Department Name
Klinik für Innere Medizin
Contact Person Name
Clara Lehmann
Contact Person Email
clara.lehmann@uk-koeln.de
Site Name
CRS Clinical Research Services Mannheim GmbH
Department Name
Clinical Pharmacology Unit
Contact Person Name
Marina Streckenbein

Sponsor

Primary sponsor

Full Name
BioNTech SE
Organisation Type
Pharmaceutical company
Country Of Registered Address
Germany

Investigational products

Investigational Product Name
BNT351
Active Substance
BNT351
Modality
Monoclonal antibody
Authorisation Status
Investigational

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