Clinical trial • Phase III • Oncology
BMS-986365 for Metastatic castration-resistant prostate cancer
Phase III trial of BMS-986365 for Metastatic castration-resistant prostate cancer.
Overview
- Trial Therapeutic Area
- Oncology
- Trial Disease
- Metastatic castration-resistant prostate cancer
- Trial Stage
- Phase III
- Drug Modality
- Small molecule
Key dates
- Initial CTIS Submission Date
- 16-01-2025
- First CTIS Authorization Date
- 02-05-2025
Trial design
Randomised, open-label, investigator's choice of therapy comprising either docetaxel (docetaxel; infusion; dose/schedule not specified) or a second androgen receptor pathway inhibitor (examples listed: abiraterone, enzalutamide; dose/schedule not specified). prednisone/prednisolone are included as comparator/supportive medicinal products (dose/schedule not specified).-controlled, adaptive Phase III trial in Czechia, Italy, France and others.
- Randomised
- Yes
- Open Label
- Yes
- Comparator
- Investigator's choice of therapy comprising either Docetaxel (docetaxel; infusion; dose/schedule not specified) OR a second androgen receptor pathway inhibitor (examples listed: Abiraterone, Enzalutamide; dose/schedule not specified). Prednisone/Prednisolone are included as comparator/supportive medicinal products (dose/schedule not specified).
- Adaptive
- True, two-part adaptive design stated ("Two-part, Randomized, Open-label, Adaptive Study"); includes dose assessment to identify the BMS-986365 dose with the best benefit–risk profile (specific adaptive rules/interim analyses not provided).
- Single Multiple Or Escalation Dose Combined
- Yes
- Target Sample Size
- 586
- Trial Duration For Participant
- 1359
Eligibility
Recruits 586 No vulnerable population selected; participants are adult men (18 years or older). Informed consent is to be provided by the participant (no assent for minors required because minors are excluded)..
- Vulnerable Population
- No vulnerable population selected; participants are adult men (18 years or older). Informed consent is to be provided by the participant (no assent for minors required because minors are excluded).
Inclusion criteria
- {"criterion_text":"- Men who are 18 years or older with a certain type of advanced prostate cancer that is getting worse."}
- {"criterion_text":"- Men who have signs of the cancer spreading to other parts of their body, which can be seen on special scans like a bone scan or a CT/MRI scan."}
- {"criterion_text":"- Questionnaires will be filled out by the participant to ensure they are not suffering too much from their prostate cancer symptoms."}
- {"criterion_text":"- Participants should have also tried certain treatments before, like abiraterone, enzalutamide, apalutamide, or darolutamide, which are medicines used to treat prostate cancer."}
Exclusion criteria
- {"criterion_text":"- There are some conditions that exclude from participation like heart problems or serious heart disease."}
- {"criterion_text":"- Also, if the cancer has spread to the brain or liver, or if a special type of bone scan called a Tc-99m superscan shows too much cancer spread, then the man can't join the trial."}
Endpoints
Primary endpoints
- {"endpoint_text":"- rPFS (for radiographic progression-free survival) by BICR (Blinded Independent Central Review). The ability of BMS-986365 to work better than other treatments chosen by the doctors is tested by looking at the rPFS, which shows how long it takes for the disease to get worse by radiographic imaging techniques (like X-rays or scans)","definition_or_measurement_approach":"Radiographic progression-free survival assessed by Blinded Independent Central Review (BICR); measured as time to radiographic disease progression using radiographic imaging techniques."}
Secondary endpoints
- {"endpoint_text":"- OS (Overall Survival) This study will assess if people live longer when they take BMS-986365 compared to other treatments chosen by the doctors. This is what is called \"Overall Survival\".","definition_or_measurement_approach":"Overall Survival measured as time from randomization to death from any cause."}
Other endpoints
- {"endpoint_text":"- To compare BMS-986365 with the doctor's chosen treatment. It will measure success by looking at how long the patients live after starting the treatment.","definition_or_measurement_approach":"Assess survival outcomes post-treatment (text provided as objective)."}
- {"endpoint_text":"- Assessing the dose of BMS-986365 that presents the best benefitrisk profile (= being able to control the cancer while keeping a good tolerance)","definition_or_measurement_approach":"Dose-finding assessment to identify dose with optimal benefit–risk; specific dose levels and rules not provided in available data."}
- {"endpoint_text":"- Evaluating the level of the drug in the blood","definition_or_measurement_approach":"Pharmacokinetic sampling and measurement of drug plasma concentrations (PK)."}
- {"endpoint_text":"- Evaluating other biological markers to see how effective is the drug","definition_or_measurement_approach":"Assessment of biomarkers (PD/biological markers) to evaluate drug effect; specifics not provided."}
- {"endpoint_text":"- Evaluating the tolerance and impact of study drugs on symptoms, overall health and quality of life.","definition_or_measurement_approach":"Safety and patient-reported outcomes (tolerability, symptoms, overall health, quality of life) using questionnaires and clinical assessments."}
Recruitment
- Planned Sample Size
- 586
- Recruitment Window Months
- 44
- Consent Approach
- Informed consent is provided by the participant (adult men 18+). Country-specific subject information sheets and informed consent forms (L1 SIS and ICF) are available for multiple countries/languages (document versions present for English, German, Italian, French, Spanish, Polish, Czech, Slovak, Swedish, Romanian and others). No assent procedures for minors (minors excluded).
Methods
- Country-specific recruitment arrangements documents (K1) present for multiple countries indicating local planned recruitment procedures (titles present for DE, IT, FR, CZ, IE, SK, AT, RO and others).
- Recruitment brochures (K2) and recruitment posters — patient-facing printed materials for outreach and site-level recruitment.
- PI-to-Patient letters (K2) — direct invitation/communication from the principal investigator to potential participants.
- Site-based recruitment through hospitals/oncology clinics (trial sites listed for each country) — local clinician referral (site-specific contact details provided).
Geography
- Total Number Of Sites
- 94
- Total Number Of Participants
- 586
Czechia
- Earliest CTIS Part Ii Submission Date
- 03-04-2025
- Latest Decision Or Authorization Date
- 30-03-2026
- Processing Time Days
- 361
- Number Of Sites
- 7
- Number Of Participants
- 28
Sites
- Site Name
- Vseobecna Fakultni Nemocnice V Praze
- Department Name
- Onkologicka klinika
- Contact Person Name
- Martin Mateju
- Contact Person Email
- martin.mateju@vfn.cz
- Site Name
- Urocentrum Praha s.r.o.
- Contact Person Name
- Michaela Matouskova
- Contact Person Email
- matouskova@urocentrum.cz
- Site Name
- Fakultni Thomayerova nemocnice
- Department Name
- Onkologicka klinika
- Contact Person Name
- Eugen Kubala
- Contact Person Email
- eugen.kubala@ftn.cz
- Site Name
- Fakultni Nemocnice V Motole
- Department Name
- Onkologicka klinika
- Contact Person Name
- Tomas Buchler
- Contact Person Email
- tomas.buchler@fnmotol.cz
- Site Name
- University Hospital Olomouc
- Department Name
- Onkologicka klinika
- Contact Person Name
- Bohuslav Melichar
- Contact Person Email
- bohuslav.melichar@fnol.cz
- Site Name
- Masarykuv Onkologicky Ustav
- Department Name
- Klinika komplexni onkologicke pece
- Contact Person Name
- Jiri Navratil
- Contact Person Email
- jiri.navratil@mou.cz
- Site Name
- Fakultni Nemocnice Hradec Kralove
- Department Name
- Klinika onkologie a radioterapie
- Contact Person Name
- Miroslav Hodek
- Contact Person Email
- miroslav.hodek@fnhk.cz
Italy
- Earliest CTIS Part Ii Submission Date
- 04-03-2025
- Latest Decision Or Authorization Date
- 30-03-2026
- Processing Time Days
- 391
- Number Of Sites
- 10
- Number Of Participants
- 35
Sites
- Site Name
- Azienda Ospedaliero-Universitaria San Luigi Gonzaga
- Department Name
- Oncologia Medica
- Contact Person Name
- Consuelo Buttigliero
- Contact Person Email
- consuelo.buttigliero@unito.it
- Site Name
- Azienda Ospedaliera S Maria Di Terni
- Department Name
- Oncologia Medica e Translazionale
- Contact Person Name
- Annalisa Guida
- Contact Person Email
- a.guida@aospterni.it
- Site Name
- San Raffaele Hospital
- Department Name
- Oncologia Medica
- Contact Person Name
- Andrea Necchi
- Contact Person Email
- necchi.andrea@hsr.it
- Site Name
- I.F.O. Istituti Fisioterapici Ospitalieri
- Department Name
- Oncologia Medica
- Contact Person Name
- Fabio Calabrò
- Contact Person Email
- fabio.calabro@ifo.it
- Site Name
- Istituto Oncologico Veneto
- Department Name
- Oncologia Medica 1
- Contact Person Name
- Umberto Basso
- Contact Person Email
- umberto.basso@iov.veneto.it
- Site Name
- IRCCS Istituto Nazionale Tumori Fondazione Pascale
- Department Name
- Oncologia Clinica Sperimentale Uro-Ginecologica
- Contact Person Name
- Sabrina Rossetti
- Contact Person Email
- s.rossetti@istitutotumori.na.it
- Site Name
- Istituto Nazionale Dei Tumori
- Department Name
- Oncologia Medica
- Contact Person Name
- Giuseppe Procopio
- Contact Person Email
- giuseppe.procopio@istitutotumori.mi.it
- Site Name
- Azienda Provinciale Per I Servizi Sanitari
- Department Name
- Oncologia Medica
- Contact Person Name
- Orazio Caffo
- Contact Person Email
- orazio.caffo@apss.tn.it
- Site Name
- Azienda Ospedaliero Universitaria Ospedali Riuniti
- Department Name
- Oncologia Medica E Terapia Biomolecolare
- Contact Person Name
- Vincenza Conteduca
- Contact Person Email
- vincenza.conteduca@unifg.it
- Site Name
- Azienda Unita' Sanitaria Locale Toscana Sud Est
- Department Name
- Oncologia Medica
- Contact Person Name
- Alketa Hamzaj
- Contact Person Email
- alketa.hamzaj@uslsudest.toscana.it
France
- Earliest CTIS Part Ii Submission Date
- 25-02-2025
- Latest Decision Or Authorization Date
- 25-03-2026
- Processing Time Days
- 393
- Number Of Sites
- 11
- Number Of Participants
- 36
Sites
- Site Name
- Les Hopitaux Universitaires De Strasbourg
- Department Name
- Oncologie Médicale
- Contact Person Name
- Philippe Barthelemy
- Contact Person Email
- p.barthelemy@icans.eu
- Site Name
- Institut De Cancerologie De Lorraine
- Department Name
- Oncologie Médicale
- Contact Person Name
- Vincent Massard
- Contact Person Email
- v.massard@nancy.unicancer.fr
- Site Name
- Centre Jean Perrin
- Department Name
- Oncologie
- Contact Person Name
- Hakim Mahammedi
- Contact Person Email
- hakim.mahammedi@clermont.unicancer.fr
- Site Name
- Institut Gustave Roussy
- Department Name
- Oncologie Médicale
- Contact Person Name
- Natacha Naoun
- Contact Person Email
- natacha.naoun@gustaveroussy.fr
- Site Name
- Institut De Cancerologie Strasbourg Europe
- Department Name
- Oncologie Médicale
- Contact Person Name
- Philippe Barthelemy
- Contact Person Email
- p.barthelemy@icans.eu
- Site Name
- Centre Antoine Lacassagne
- Department Name
- Oncologie Médicale
- Contact Person Name
- Delphine Borchiellini
- Contact Person Email
- delphine.borchiellini@nice.unicancer.fr
- Site Name
- Centre Hospitalier Prive Saint-Gregoire
- Department Name
- Oncologie Médicale
- Contact Person Name
- Aurélien Gobert
- Contact Person Email
- aurelien.gobert@icrb.fr
- Site Name
- Clinique Victor Hugo
- Department Name
- Oncologie Radiothérapie
- Contact Person Name
- Amandine Ruffier
- Contact Person Email
- essaisruffier@ilcgroupe.fr
- Site Name
- Oncopole Claudius Regaud
- Department Name
- Oncologie Médicale
- Contact Person Name
- Loïc Mourey
- Contact Person Email
- mourey.loic@iuct-oncopole.fr
- Site Name
- Centr Georges Francois Leclerc
- Department Name
- Oncologie Médicale
- Contact Person Name
- Sylvain Ladoire
- Contact Person Email
- sladoire@cgfl.fr
- Site Name
- Hospices Civils De Lyon
- Department Name
- Oncologie Médicale
- Contact Person Name
- Denis Maillet
- Contact Person Email
- denis.maillet@chu-lyon.fr
Poland
- Earliest CTIS Part Ii Submission Date
- 07-02-2025
- Latest Decision Or Authorization Date
- 31-03-2026
- Processing Time Days
- 417
- Number Of Sites
- 8
- Number Of Participants
- 39
Sites
- Site Name
- Wojewodzki Szpital Specjalistyczny Nr 4 W Bytomiu Samodzielny Publiczny Zaklad Opieki Zdrowotnej
- Department Name
- Oddział Onkologii Klinicznej
- Contact Person Name
- Ewa Nowakowska-Zajdel
- Contact Person Email
- s.onkologia@szpital4.bytom.pl
- Site Name
- Pratia S.A.
- Department Name
- Pratia Poznan
- Contact Person Name
- Marek Kotlarski
- Contact Person Email
- marek.kotlarski@pratia.com
- Site Name
- Polimed Specjalistyczna Przychodnia Lekarska
- Contact Person Name
- Krzysztof Tupikowski
- Contact Person Email
- tupikowski@poczta.onet.pl
- Site Name
- Opolskie Centrum Onkologii Im. Prof. Tadeusza Koszarowskiego W Opolu Samodzielny Publiczny Zaklad Opieki Zdrowotnej
- Department Name
- Klinika Onkologii z Odcinkiem Dziennym
- Contact Person Name
- Barbara Radecka
- Contact Person Email
- brad@onkologia.opole.pl
- Site Name
- Centrum Onkologii Im. Prof. Franciszka Lukaszczyka W Bydgoszczy
- Department Name
- Ambulatorium Chemioterapii
- Contact Person Name
- Bogdan Zurawski
- Contact Person Email
- zurawski@co.bydgoszcz
- Site Name
- Panstwowy Instytut Medyczny Ministerstwa Spraw Wewnetrznych I Administracji
- Department Name
- Oddział Terapii Izotopowej
- Contact Person Name
- Bartosz Itrych
- Contact Person Email
- bartosz.itrych@cskmswia.gov.pl
- Site Name
- Copernicus Podmiot Leczniczy Sp. z o.o.
- Department Name
- Wojewodzkie Centrum Onkologii Oddzial Onkologii Klinicznej/ Chemioterapii
- Contact Person Name
- Joanna Wojcik-Tomaszewska
- Contact Person Email
- sekretariat.wco@copernicus.gda.pl
- Site Name
- Pratia Hematologia Sp. z o.o.
- Department Name
- Pratia Onkologia Katowice
- Contact Person Name
- Agata Kachel-Flis
- Contact Person Email
- agata.kachel-flis@pratia.com
Ireland
- Earliest CTIS Part Ii Submission Date
- 10-04-2025
- Latest Decision Or Authorization Date
- 05-05-2026
- Processing Time Days
- 390
- Number Of Sites
- 3
- Number Of Participants
- 13
Sites
- Site Name
- Beaumont Hospital
- Department Name
- Medical Oncology
- Contact Person Name
- MinYuen Teo
- Contact Person Email
- minyuenteo@beaumont.ie
- Site Name
- Tallaght University Hospital
- Department Name
- Medical Oncology
- Contact Person Name
- Ray McDermott
- Contact Person Email
- ray.mcdermott@tuh.ie
- Site Name
- Cork University Hospital
- Department Name
- Medical Oncology
- Contact Person Name
- Jack Gleeson
- Contact Person Email
- Jack.Gleeson@hse.ie
Germany
- Earliest CTIS Part Ii Submission Date
- 04-04-2025
- Latest Decision Or Authorization Date
- 27-03-2026
- Processing Time Days
- 357
- Number Of Sites
- 14
- Number Of Participants
- 48
Sites
- Site Name
- Universitaetsklinikum Heidelberg AöR
- Department Name
- Abt. Medizinische Onkologie
- Contact Person Name
- Stefanie Zschäbitz
- Contact Person Email
- stefanie.zschaebitz@med.uni-heidelberg.de
- Site Name
- Universitaetsklinikum Jena KöR
- Department Name
- Klinik und Poliklinik für Urologie
- Contact Person Name
- Marc-Oliver Grimm
- Contact Person Email
- marc-oliver.grimm@med.uni-jena.de
- Site Name
- Universitaetsklinikum Wuerzburg AöR
- Department Name
- Klinik und Poliklinik für Urologie und Kinderurologie
- Contact Person Name
- Hubert Kübler
- Contact Person Email
- kuebler_h@ukw.de
- Site Name
- Urologicum Duisburg
- Department Name
- Studienzentrum
- Contact Person Name
- Eva Hellmis
- Contact Person Email
- hellmis@urologicum-duisburg.de
- Site Name
- St. Marien-Krankenhaus GmbH
- Department Name
- Urologie & Kinderurologie - Studienzentrum
- Contact Person Name
- Stefan Machtens
- Contact Person Email
- stefan.machtens@mkh-bgl.de
- Site Name
- Universitaetsklinikum Schleswig-Holstein AöR
- Department Name
- Klinik für Urologie
- Contact Person Name
- Axel Merseburger
- Contact Person Email
- axel.merseburger@uksh.de
- Site Name
- St. Elisabeth Gruppe GmbH Katholische Kliniken Rhein-Ruhr
- Department Name
- Klinik für Urologie
- Contact Person Name
- Florian Roghmann
- Contact Person Email
- florian.roghmann@elisabethgruppe.de
- Site Name
- Urologisches Zentrum Mittelhessen - Praxis Biedenkopf
- Department Name
- Studien
- Contact Person Name
- Axel Hegele
- Contact Person Email
- hegele@urologie-mittelhessen.de
- Site Name
- Universitaetsklinikum Essen AöR
- Department Name
- Klinik für Urologie
- Contact Person Name
- Claudia Kesch
- Contact Person Email
- claudia.kesch@uk-essen.de
- Site Name
- Studienpraxis Urologie Susan Feyerabend MD Tilman Todenhoefer MD PhD GbR
- Department Name
- Studienzentrum
- Contact Person Name
- Tilman Todenhöfer
- Contact Person Email
- praxis@studienurologie.de
- Site Name
- Klinikum der Technischen Universitaet Muenchen (TUM Klinikum)
- Department Name
- Klinik und Poliklinik für Urologie
- Contact Person Name
- Margitta Retz
- Contact Person Email
- margitta.retz@tum.de
- Site Name
- Universitaetsklinikum Bonn AöR
- Department Name
- Klinik und Poliklinik für Urologie und Kinderurologie
- Contact Person Name
- Manuel Ritter
- Contact Person Email
- mritter@ukbonn.de
- Site Name
- University Medical Center Hamburg-Eppendorf
- Department Name
- II. Medizinische Klinik und Poliklinik
- Contact Person Name
- Gunhild von Amsberg
- Contact Person Email
- g.von-amsberg@uke.de
- Site Name
- Universitaetsklinikum Tuebingen AöR
- Department Name
- Universitätsklinik für Urologie
- Contact Person Name
- Steffen Rausch
- Contact Person Email
- steffen.rausch@med.uni-tuebingen.de
Romania
- Earliest CTIS Part Ii Submission Date
- 07-02-2025
- Latest Decision Or Authorization Date
- 06-04-2026
- Processing Time Days
- 423
- Number Of Sites
- 5
- Number Of Participants
- 25
Sites
- Site Name
- Institutul Regional De Oncologie Iasi
- Department Name
- Oncologie Medicala
- Contact Person Name
- Teodora Alexa-Stratulat
- Contact Person Email
- manager@iroiasi.ro
- Site Name
- Institute Of Oncology Prof. Dr. Ion Chiricuta Cluj-Napoca
- Department Name
- Oncologie Medicala
- Contact Person Name
- Tudor-Eliade Ciuleanu
- Contact Person Email
- office@iocn.ro
- Site Name
- Spitalul Municipal Ploiesti
- Department Name
- Oncologie Medicala
- Contact Person Name
- Nita Amedeia
- Contact Person Email
- spitalschuller@yahoo.com
- Site Name
- Centrul De Oncologie SF Nectarie S.R.L.
- Department Name
- Oncologie Medicala
- Contact Person Name
- Michael Schenker
- Contact Person Email
- office@centruldeoncologie.ro
- Site Name
- CF Clinical Hospital
- Department Name
- Oncologie Medicala
- Contact Person Name
- Anca Mihailov
- Contact Person Email
- spitalcliniccfcluj@gmail.com
Spain
- Earliest CTIS Part Ii Submission Date
- 17-03-2025
- Latest Decision Or Authorization Date
- 30-03-2026
- Processing Time Days
- 378
- Number Of Sites
- 20
- Number Of Participants
- 73
Sites
- Site Name
- Hospital Universitario Reina Sofia
- Department Name
- Oncology
- Contact Person Name
- Maria Jose Mendez Vidal
- Contact Person Email
- xxx.xxx@xxx.es
- Site Name
- Complejo Hospitalario Universitario De Ourense
- Department Name
- Oncology
- Contact Person Name
- Ovidio Fernandez Calvo
- Contact Person Email
- xxx.xxx@xxx.es
- Site Name
- Hospital General Universitario Gregorio Maranon
- Department Name
- Oncology
- Contact Person Name
- Jose Angel Arranz Arija
- Contact Person Email
- xxx.xxx@xxx.es
- Site Name
- Parc Tauli Hospital Universitari
- Department Name
- Oncology
- Contact Person Name
- Enrique Gallardo Diaz
- Contact Person Email
- egallardo@tauli.cat
- Site Name
- Hospital Universitario Puerta De Hierro De Majadahonda
- Department Name
- Oncology
- Contact Person Name
- Aranzazu Gonzalez del Alba
- Contact Person Email
- xxx.xxx@xxx.es
- Site Name
- Hospital Universitario Vithas La Salud
- Department Name
- Oncology
- Contact Person Name
- Pedro Sanchez Rovira
- Contact Person Email
- xxx.xxx@xxx.es
- Site Name
- Hospital Universitario Ramon Y Cajal
- Department Name
- Oncology
- Contact Person Name
- Teresa Alonso Gordoa
- Contact Person Email
- xxx.xxx@xxx.es
- Site Name
- Hospital Universitari Vall D Hebron
- Department Name
- Oncology
- Contact Person Name
- Joaquin Mateo Valderrama
- Contact Person Email
- xxx.xxx@xxx.es
- Site Name
- Hospital Universitario La Paz
- Department Name
- Oncology
- Contact Person Name
- Alvaro Pinto Marin
- Contact Person Email
- xxx.xxx@xxx.es
- Site Name
- Hospital Universitario De Badajoz
- Department Name
- Oncology
- Contact Person Name
- Marta Gonzalez Cordero
- Contact Person Email
- xxx.xxx@xxx.es
- Site Name
- Hospital Universitario Lucus Augusti
- Department Name
- Oncology
- Contact Person Name
- Sergio Vazquez Estevez
- Contact Person Email
- sergio.vazquez.estevez@sergas.es
- Site Name
- Hospital Universitario 12 De Octubre
- Department Name
- Oncology
- Contact Person Name
- Daniel Castellano Gauna
- Contact Person Email
- xxx.xxx@xxx.es
- Site Name
- Hospital Universitario De Cruces
- Department Name
- Oncology
- Contact Person Name
- Ricardo Fernandez Rodriguez
- Contact Person Email
- ricardo.fernandezrodriguez@osakidetza.eus
- Site Name
- Hospital Universitario De Navarra
- Department Name
- Oncology
- Contact Person Name
- Nuria Lainez Milagro
- Contact Person Email
- nuria.lainez.milagro@navarra.es
- Site Name
- Hospital Universitario Virgen De La Macarena
- Department Name
- Oncology
- Contact Person Name
- Alvaro Sanchez Camacho Mejias
- Contact Person Email
- xxx.xxx@xxx.es
- Site Name
- University Hospital Virgen Del Rocio S.L.
- Department Name
- Oncology
- Contact Person Name
- Begona Perez Valderrama
- Contact Person Email
- xxx.xxx@xxx.es
- Site Name
- Hospital De La Santa Creu I Sant Pau
- Department Name
- Oncology
- Contact Person Name
- Jose Pablo Maroto Rey
- Contact Person Email
- jmaroto@santpau.cat
- Site Name
- Hospital Clinico San Carlos
- Department Name
- Oncology
- Contact Person Name
- Javier Puente Vazquez
- Contact Person Email
- javierpuente.hcsc@gmail.com
- Site Name
- Hospital Universitario De Burgos
- Department Name
- Oncology
- Contact Person Name
- Guillermo Crespo Herrero
- Contact Person Email
- xxx.xxx@xxx.es
- Site Name
- Hospital Universitario Y Politecnico La Fe
- Department Name
- Oncology
- Contact Person Name
- Regina Girones Sarrio
- Contact Person Email
- girones_reg@gva.es
Austria
- Earliest CTIS Part Ii Submission Date
- 24-03-2025
- Latest Decision Or Authorization Date
- 17-04-2026
- Processing Time Days
- 389
- Number Of Sites
- 4
- Number Of Participants
- 18
Sites
- Site Name
- Gemeinnuetzige Salzburger Landeskliniken Betriebsgesellschaft mbH
- Department Name
- University Clinic for Urology and Andrology
- Contact Person Name
- Lukas Oberhammer
- Contact Person Email
- l.oberhammer@salk.at
- Site Name
- Medical University Of Vienna
- Department Name
- University Clinic for Urology
- Contact Person Name
- Gero Kramer
- Contact Person Email
- gero.kramer@meduniwien.ac.at
- Site Name
- Ordensklinikum Linz GmbH
- Department Name
- Department of Urology
- Contact Person Name
- Ferdinand Luger
- Contact Person Email
- ferdinand.luger@ordensklinikum.at
- Site Name
- Universitaetsklinikum Krems
- Department Name
- Clinical Department of Internal Medicine 2
- Contact Person Name
- Sonia Vallet
- Contact Person Email
- sonia.vallet@krems.lknoe.at
Slovakia
- Earliest CTIS Part Ii Submission Date
- 01-08-2025
- Latest Decision Or Authorization Date
- 04-05-2026
- Processing Time Days
- 276
- Number Of Sites
- 4
- Number Of Participants
- 16
Sites
- Site Name
- F D Roosevelt University General Hospital Of Banska Bystrica
- Department Name
- Oncology
- Contact Person Name
- Matej Hrncar
- Contact Person Email
- mhrncar@nspbb.sk
- Site Name
- Urologia s.r.o.
- Department Name
- Urologia
- Contact Person Name
- Jan Kliment
- Contact Person Email
- jan.kliment@uniba.sk
- Site Name
- Milab s.r.o.
- Department Name
- Urology
- Contact Person Name
- Ivan Mincik
- Contact Person Email
- maria.mincikova@gmail.com
- Site Name
- Narodny Onkologicky Ustav
- Department Name
- Oncology
- Contact Person Name
- Michal Mego
- Contact Person Email
- daniela.svetlovska@nou.sk
Sweden
- Earliest CTIS Part Ii Submission Date
- 08-04-2025
- Latest Decision Or Authorization Date
- 26-03-2026
- Processing Time Days
- 352
- Number Of Sites
- 4
- Number Of Participants
- 23
Sites
- Site Name
- Karolinska University Hospital
- Department Name
- Medicinsk enhet Bäckencancer, urologisk onkologi, A5:01 Mottagning Urologiska sjukdomar
- Contact Person Name
- Enrique Castellanos
- Contact Person Email
- enrique.castellanos@regionstockholm.se
- Site Name
- Region Skane Skanes Universitetssjukhus
- Department Name
- VO Hematologi, Onkologi och Strålningsfysik
- Contact Person Name
- Olof Stahl
- Contact Person Email
- olof.stahl@skane.se
- Site Name
- Sahlgrenska University Hospital-Vaestra Goetalandsregionen
- Department Name
- Onkologkliniken
- Contact Person Name
- Jon Kindblom
- Contact Person Email
- jon.kindblom@vgregion.se
- Site Name
- Uppsala University Hospital
- Department Name
- Onkologkliniken
- Contact Person Name
- Ingrida Verbiene
- Contact Person Email
- ingrida.verbiene@akademiska.se
Denmark
- Earliest CTIS Part Ii Submission Date
- 29-04-2025
- Latest Decision Or Authorization Date
- 30-03-2026
- Processing Time Days
- 330
- Number Of Sites
- 4
- Number Of Participants
- 20
Sites
- Site Name
- Region Hovedstaden
- Department Name
- Urology
- Contact Person Name
- Rasmus Bisbjerg
- Contact Person Email
- rasmus.bisbjerg@regionh.dk
- Site Name
- Aarhus University Hospital
- Department Name
- Oncology
- Contact Person Name
- simon Buus
- Contact Person Email
- simon.buus@auh.rm.dk
- Site Name
- Rigshospitalet
- Department Name
- Oncology
- Contact Person Name
- Gedske Daugaard
- Contact Person Email
- kirsten.gedske.daugaard@regionh.dk
- Site Name
- Aalborg University Hospital
- Department Name
- Oncology
- Contact Person Name
- Mette Moe
- Contact Person Email
- mmk@rn.dk
Sponsor
Primary sponsor
- Full Name
- Celgene Corporation
- Organisation Type
- Pharmaceutical company
- Country Of Registered Address
- United States
Third parties
- {"country":"United States","full_name":"RWS Life Sciences Inc.","duties_or_roles":"Licensing and translation services","organisation_type":"Pharmaceutical company"}
- {"country":"United States","full_name":"Foundation Medicine Inc.","duties_or_roles":"Genomic Analysis, Tumor Mutational Burden analysis","organisation_type":"Pharmaceutical company"}
- {"country":"United States","full_name":"Signant Health Global LLC","duties_or_roles":"Subject Number assignment, Treatment/Arm assignment,Drug (re)supplies assignment, PRO/COA","organisation_type":"Pharmaceutical company"}
- {"country":"United States","full_name":"Yprime LLC","duties_or_roles":"Core Technology Services","organisation_type":"Non-Pharmaceutical company"}
- {"country":"United States","full_name":"QPS LLC","duties_or_roles":"TS and BioA","organisation_type":"Pharmaceutical company"}
- {"country":"Denmark","full_name":"Nordic Bioscience A/S (Herlev Hovedgade 205)","duties_or_roles":"Speciality Biomarker Laboratory","organisation_type":"Pharmaceutical company"}
- {"country":"Denmark","full_name":"Nordic Bioscience A/S (Herlev Hovedgade 207)","duties_or_roles":"Speciality Biomarker Laboratory","organisation_type":"Pharmaceutical company"}
- {"country":"India","full_name":"Accenture Solutions Private Limited","duties_or_roles":"Embarc operations","organisation_type":"Pharmaceutical company"}
Investigational products
- Investigational Product Name
- BMS-986365
- Active Substance
- BMS-986365
- Modality
- Small molecule
- Routes Of Administration
- ORAL
- Route
- ORAL
- Authorisation Status
- Investigational product (IMP)
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